Estrogen Receptor (ER) Alpha Regulatory Mechanisms and Therapeutic Strategies in ER+ Breast Cancer, Bianca A. Romo
Dartmouth College Ph.D Dissertations

Regulation of the Wnt/Wingless receptor LRP6/Arrow by the deubiquitylating complex Usp46, Zachary T. Spencer
Dartmouth College Ph.D Dissertations

Cell-Typing and Interaction Analysis of the Immune Compartment of the Tumor Microenvironment using High-Resolution Omics Modalities, Courtney Taylor Schiebout
Dartmouth College Ph.D Dissertations

UNDERSTANDING THE IMPLICATIONS OF LINEAGE PLASTICITY IN BREAST CANCER EVOLUTION AND CHEMOTHERAPY RESPONSE, Gadisti Aisha Mohamed
Dartmouth College Ph.D Dissertations

Characterization of cell type-specific molecular heterogeneity in cancer using multi-omic approaches, Min Kyung Lee
Dartmouth College Ph.D Dissertations

THE ROLES OF EPITHELIAL–MESENCHYMAL PLASTICITY IN TUMOR HETEROGENEITY, METASTASIS, AND PATIENT SURVIVAL IN BREAST CANCER, Meredith Septer Brown
Dartmouth College Ph.D Dissertations

A Machine Learning Classifier Trained on Cancer Transcriptomes Detects NF1 Inactivation Signal in Glioblastoma, Gregory P. Way, Robert J. Allaway, Stephanie J. J. Bouley, Camilo E. Fadul, Yolanda Sanchez, Casey Greene
Dartmouth Scholarship

Comparative Genetic Screens in Human Cells Reveal New Regulatory Mechanisms in WNT Signaling, Andres M. Lebensohn, Ramin Dubey, Leif Neitzel, Ofelia Tacchelly-Benites
Dartmouth Scholarship

The ADP-Ribose Polymerase Tankyrase Regulates Adult Intestinal Stem Cell Proliferation During Homeostasis in Drosophila, Zhenghan Wang, Ai Tian, Hassina Benchabane, Ofelia Tacchelly-Benites, Eungi Yang, Hisashi Nojima, Yashi Ahmed
Dartmouth Scholarship

Targeting Neddylation Induces DNA Damage and Checkpoint Activation and Sensitizes Chronic Lymphocytic Leukemia B Cells to Alkylating Agents, C Paiva, J C. Godbersen, A Berger, J R. Brown, A V. Danilov
Dartmouth Scholarship

Synthetic Triterpenoids Can Protect Against Toxicity Without Reducing the Efficacy of Treatment with Carboplatin and Paclitaxel in Experimental Lung Cancer, Karen T. Liby
Dartmouth Scholarship

Sensitization of Human Cancer Cells to Gemcitabine by the Chk1 Inhibitor MK-8776: Cell Cycle Perturbation and Impact of Administration Schedule in Vitro and in Vivo, Ryan Montano, Ruth Thompson, Injae Chung, Huagang Hou, Nadeem Khan, Alan Eastman
Dartmouth Scholarship

KillerFLIP: A Novel Lytic Peptide Specifically Inducing Cancer Cell Death, B Pennarun, G. Gaidos, O Bucur, A Tinari
Dartmouth Scholarship

PV1 Down-Regulation via shRNA Inhibits the Growth of Pancreatic Adenocarcinoma Xenografts, Sophie J. Deharvengt, Dan Tse, Olga Sideleva, Caitlin McGarry, Jason R. Gunn, Daniel S. Longnecker, Catherine Carriere, Radu V. Stan
Dartmouth Scholarship

Interleukin-1β Mediates Metalloproteinase-Dependent Renal Cell Carcinoma Tumor Cell Invasion through the Activation of CCAAT Enhancer Binding Protein β, Brenda L. Petrella, Matthew P. P. Vincenti
Dartmouth Scholarship

Cdk1 and Plk1 mediate a CLASP2 Phospho-Switch that Stabilizes Kinetochore–Microtubule Attachments, Ana R. R. Maia, Zaira Garcia, Lilian Kabeche, Marin Barisic
Dartmouth Scholarship

Variations in Mre11/Rad50/Nbs1 Status and DNA Damage-Induced S-Phase Arrest in the Cell Lines of the NCI60 Panel, Kristen M. K. Garner, Alan Eastman
Dartmouth Scholarship

CD277 is a Negative Co-stimulatory Molecule Universally Expressed by Ovarian Cancer Microenvironmental Cells, Juan R. Cubillos-Ruiz, Diana Martinez, Uciane K. Scarlett, Melanie R. Rutkowski, Yolanda C. Nesbeth, Ana L. Camposeco-Jacobs, Jose R. Conejo-Garcia
Dartmouth Scholarship

Wnt Pathway Reprogramming During Human Embryonal Carcinoma Differentiation and Potential for Therapeutic Targeting, Grace E. Snow, Allison C. Kasper, Alexander M. Busch, Elisabeth Schwarz, Katherine E. Ewings, Thomas Bee, Michael J. Spinella, Ethan Dmitrovsky, Sarah J. Freemantle
Dartmouth Scholarship

Growth Factor–Induced Shedding of Syndecan-1 Confers Glypican-1 Dependence on Mitogenic Responses of Cancer Cells, Kan Ding, Martha Lopez-Burks, José A. Sánchez-Duran, Murray Korc, Arthur D. Lander
Dartmouth Scholarship

UBE1L is a Retinoid Target that Triggers PML/RARα Degradation and Apoptosis in Acute Promyelocytic Leukemia, Sutisak Kitareewan, Ian Pitha-Rowe, David Sekula, Christopher H. Lowrey, Michael J. Nemeth, Todd R. Golub, Sarah J. Freemantle, Ethan Dmitrovsky
Dartmouth Scholarship