Structure-based targeting of the NEMO:IKK interaction for canonical NF-κB inhibition, Amy Kennedy
Dartmouth College Ph.D Dissertations

Mitochondrial Quality Control by Tail-Anchored Proteins, Jose M. Delgado
Dartmouth College Ph.D Dissertations

Molecular Mechanisms Regulating Prometaphase and Metaphase States for Faithful Chromosome Segregation, Sarah Yvette Valles
Dartmouth College Ph.D Dissertations

PROTEOMIC APPROACHES TO IDENTIFY UNIQUE AND SHARED SUBSTRATES AMONG KINASE FAMILY MEMBERS, Charles Lincoln Howarth
Dartmouth College Ph.D Dissertations

Investigating the Structure of NEMO-I65M Binding with Shikonin, Tanyawan Wongsri, Amy Kennedy, Pepper Pennington, Maria Pellegrini, Dale Mierke
Wetterhahn Science Symposium Posters 2023

Structural Files for the ETR1 Ethylene-Receptor Dimer Based on Computational Modeling, Beenish J. Azhar, Safdar Abbas, Sitwat Aman, Maria V. Yamburenko, Wei Chen, Lena Muller, Buket Uzun, David A. Jewell, Jian Dong, Samina N. Shakeel, Georg Groth, Brad M. Binder, Gevorg Grigoryan, G. Eric Schaller
Dartmouth Scholarship

Novel mechanistic insight into ciliary regulation: old pathways yield new mechanisms, Larissa L. Dougherty
Dartmouth College Ph.D Dissertations

Molecular Mechanisms of Wild-type and Mutant Prion Formation, Daniel J. Walsh
Dartmouth College Ph.D Dissertations

MITOCHONDRIAL DIVISION: SYNERGIZING IN MITOCHONDRIAL DIVISOME, Ao Liu
Dartmouth College Ph.D Dissertations

DECIPHERING PHOSPHOPROTEIN PHOSPHATASE SIGNALING NETWORKS USING PROTEOMICS APPROACHES, Brooke Brauer
Dartmouth College Ph.D Dissertations

Cysteine Metallochemistry and Metal Binding: Quantification of the Thermodynamic Foundations of Cellular Homeostasis, Matthew R. Mehlenbacher
Dartmouth College Ph.D Dissertations

A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues, Shawn M. Lyons, Clark H. Cunningham, Joshua D. Welch, Beezly Groh, Andrew Y. Guo, Bruce Wei, Michael L. Whitfield, Yue Xiong, Wiliam Marzluff
Dartmouth Scholarship

Unsupervised gene set testing based on random matrix theory, H Robert Frost, Christopher I. Amos
Dartmouth Scholarship

Reference-free deconvolution of DNA methylation data and mediation by cell composition effects, E. Andres Houseman, Molly L. Kile, David C. Christiani, Tan A. Ince, Karl T. Kelsey, Carmen J. Marsit
Dartmouth Scholarship

Period-1 Encodes an ATP-Dependent RNA Helicase that Influences Nutritional Compensation of the Neurospora Circadian Clock, Jillian M. Emerson, Bradley M. Bartholomai, Carol S. Ringelberg, Scott E. Baker, Jennifer Loros, Jay Dunlap
Dartmouth Scholarship

Alternative Use of DNA Binding Domains by the Neurospora White Collar Complex Dictates Circadian Regulation and Light Responses, Bin Wang, Xiaoying Zhou, Jennifer J. Loros, Jay C. Dunlap
Dartmouth Scholarship

Actin Filaments Target the Oligomeric Maturation of the Dynamin Gtpase Drp1 to Mitochondrial Fission Sites, Wei-ke Ji, Anna L. Hatch, Ronald A. Merrill, Stefan Strack, Henry N. Higgs
Dartmouth Scholarship

Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity, Arko Dasgupta, Chen-Hui Chen, ChangHwan Lee, Amy S. Gladfelter, Jay C. Dunlap, Jennifer J. Loros
Dartmouth Scholarship

Synthesis of Bioinspired Carbohydrate Amphiphiles that Promote and Inhibit Biofilms, Eric L. Dane, Alicia E. Ballok, George A. O'Toole, Mark W. Grinstaff
Dartmouth Scholarship

Stoichiometries and Affinities of Interacting Proteins from Concentration Series of Solution Scattering Data: Decomposition by Least Squares and Quadratic Optimization, Himanshu Chandola, Tim E. Williamson, Bruce A. Craig, Alan M. Friedman, Chris Bailey-Kellogg
Dartmouth Scholarship

Redox-Dependent Stability, Protonation, and Reactivity of Cysteine-Bound Heme Proteins, Fangfang Zhong, George P. Lisi, Daniel P. Collins, John H. Dawson, Ekaterina V. Pletneva
Dartmouth Scholarship

KillerFLIP: A Novel Lytic Peptide Specifically Inducing Cancer Cell Death, B Pennarun, G. Gaidos, O Bucur, A Tinari
Dartmouth Scholarship

Bioengineered Lysozyme Reduces Bacterial Burden and Inflammation in a Murine Model of Mucoid Pseudomonas aeruginosa Lung Infection, Charlotte C. Teneback, Thomas C. Scanlon, Matthew J. Wargo, Jenna L. Bement, Karl E. Griswold, Laurie W. Leclair
Dartmouth Scholarship

How Long is a Piece of Loop?, Yoonjoo Choi, Sumeet Agarwal, Charlotte M. Deane
Dartmouth Scholarship

Force Generation by Kinesin and Myosin Cytoskeletal Motor Proteins, F. Jon Kull, Sharyn A. Endow
Dartmouth Scholarship

Insights into mRNP Biogenesis Provided by New Genetic Interactions Among Export and Transcription Factors, Francisco Estruch, Christine Hodge, Natalia Gómez-Navarro, Lorena Peiró-Chova, Catherine V. Heath, Charles N. Cole
Dartmouth Scholarship

N-Terminal Domain of Vacuolar SNARE Vam7p Promotes Trans-SNARE Complex Assembly, Hao Xu, William T. Wickner
Dartmouth Scholarship

Cdk1 and Plk1 mediate a CLASP2 Phospho-Switch that Stabilizes Kinetochore–Microtubule Attachments, Ana R. R. Maia, Zaira Garcia, Lilian Kabeche, Marin Barisic
Dartmouth Scholarship

Domain Architecture of a Calcium-Permeable AMPA Receptor in a Ligand-Free Conformation, Charles R. Midgett, Avinash Gill, Dean R. Madden
Dartmouth Scholarship

Conformational Properties of Cardiolipin-Bound Cytochrome C, Jonas Hanske, Jason R. Toffey, Anna M. Morenz, Amber J. Bonilla, Katherine H. Schiavoni;, Ekaterina V. Pletneva
Dartmouth Scholarship

Planning Combinatorial Disulfide Cross-Links for Protein Fold Determination, Fei Xiong, Alan M Friedman, Chris Bailey-Kellogg
Dartmouth Scholarship

A Lipid-Anchored SNARE Supports Membrane Fusion, Hao Xu, Michael Zick, William T. Wickner, Youngsoo Jun
Dartmouth Scholarship

Mutant Alcohol Dehydrogenase Leads to Improved Ethanol Tolerance in Clostridium Thermocellum, Steven D. Brown, Adam M. Guss, Tatiana V. Karpinets, Jerry M. Parks
Dartmouth Scholarship

Physical Interaction Between VIVID and White Collar Complex Regulates Photoadaptation in Neurospora, Chen-Hui H. Chen, Bradley S. DeMay, Amy S. Gladfelter, Jay Dunlap, Jennifer J. Loros
Dartmouth Scholarship

Genetic and Molecular Characterization of a Cryptochrome from the Filamentous Fungus Neurospora Crassa, Allan C. Froehlich, Chen-Hui Chen, William J. Belden, Cornelia Madeti
Dartmouth Scholarship

Integral Membrane Proteins Brr6 and Apq12 Link Assembly of the Nuclear Pore Complex to Lipid Homeostasis in the Endoplasmic Reticulum, Christine A. Hodge, Vineet Choudhary, Michael J. Wolyniak, John J. Scarcelli, Roger Schneiter, Charles N. Cole
Dartmouth Scholarship

Microbial NAD Metabolism: Lessons from Comparative Genomics, Francesca Gazzaniga, Rebecca Stebbins, Sheila Z. Chang, Mark A. McPeek, Charles Brenner
Dartmouth Scholarship

Insulin Stimulates the Phosphorylation of the Exocyst Protein Sec8 in Adipocytes, Patrick D. Lyons, Grantley R. Peck, Arminja N. Kettenbach, Scott A. Gerber, Liya Roudaia, Gustav E. Lienhard
Dartmouth Scholarship

Pathogenic Adaptation of Intracellular Bacteria by Rewiring a Cis-Regulatory Input Function, Suzanne E. Osborne, Don Walthers, Ana M. Tomljenovic, David T. Mulder, Uma Silphaduang, Nancy Duong, Michael J. Lowden
Dartmouth Scholarship

A Conserved CaM- and Radial Spoke–Associated Complex Mediates Regulation of Flagellar Dynein Activity, Erin E. Dymek, Elizabeth F. Smith
Dartmouth Scholarship

The Yeast Integral Membrane Protein Apq12 Potentially Links Membrane Dynamics to Assembly of Nuclear Pore Complexes, John J. Scarcelli, Christin A. Hodge, Charles N. Cole
Dartmouth Scholarship

Stoichiometric Controls of Mercury Dilution by Growth, Roxanne Karimi, Celia Y. Chen, Paul C. Pickhardt, Nicholas S. Fisher, Carol L. Folt
Dartmouth Scholarship

The Yeast Orthologue of GRASP65 Forms a Complex with a Coiled-Coil Protein that Contributes to ER to Golgi Traffic, Rudy Behnia, Francis A. Barr, John J. Flanagan, Charles Barlowe, Sean Munro
Dartmouth Scholarship

The Allantois and Chorion, when Isolated before Circulation or Chorio-Allantoic Fusion, have Hematopoietic Potential, Brandon M. Zeigler, Daisuke Sugiyama, Michael Chen, Yalin Guo, K. M. Downs, N. A. Speck
Dartmouth Scholarship

Dictyostelium Myosin-IE Is a Fast Molecular Motor Involved in Phagocytosis, Ulrike Durrwang, Setsuko Fujita-Becker, Muriel Erent, F. Jon Kull
Dartmouth Scholarship

The KinI kinesin Kif2a is required for Bipolar Spindle Assembly through a Functional Relationship with MCAK, Neil J. Ganem, Duane A. Compton
Dartmouth Scholarship

Resolution of Organelle Docking and Fusion Kinetics in a Cell-Free Assay, Alexey J. Merz, William T. Wickner
Dartmouth Scholarship

Disulfide Bond Formation Involves a Quinhydrone-Type Charge–Transfer Complex, James Regeimbal, Stefan Gleiter, Bernard L. Trumpower, Chang-Ang Yu
Dartmouth Scholarship

A Role for Yip1p in COPII Vesicle Biogenesis, Matthew Heidtman, Catherine Z. Chen, Ruth N. Collins, Charles Barlowe
Dartmouth Scholarship

Minus-End Capture of Preformed Kinetochore Fibers Contributes to Spindle Morphogenesis, Alexey Khodjakov, Lily Copenagle, Michael B. Gordon, Duane A. Compton, Tarun M. Kapoor
Dartmouth Scholarship

A Role for the Light-Dependent Phosphorylation of Visual Arrestin, Paul G. Alloway, Patrick J. Dolph
Dartmouth Scholarship

Cbfa2 is Required for the Formation of Intra-Aortic Hematopoietic Clusters, Trista North, Ting-Lei Gu, Stacy Terryl, Qing Wang, Louisa Howard, Michael Binder, Miguel Marín-Padilla, Nancy A. Speck
Dartmouth Scholarship

ETS-Core Binding Factor: a Common Composite Motif in Antigen Receptor Gene Enhancers, Batu Erman, Marta Cortes, Barbara S. Nikolajczyk, Nancy A. Speck, Ranjan Sen
Dartmouth Scholarship

A Heterodimer of Thioredoxin and IB2 Cooperates with Sec18p (NSF) to Promote Yeast Vacuole Inheritance, Zuoyu Xu, Andreas Mayer, Eric Muller, William Wickner
Dartmouth Scholarship

Circadian Clock-Controlled Genes Isolated from Neurospora Crassa are Late Night- To Early Morning-Specific, Deborah Bell-Pedersen, Mari L. Shinohara, Jennifer J. Loros, Jay C. Dunlap
Dartmouth Scholarship

NuMA Assembles Into an Extensive Filamentous Structure When Expressed in the Cell Cytoplasm, Alejandro Saredi, Louisa Howard, Duane A. Compton
Dartmouth Scholarship

Cloning of Human Acetyl-CoA Carboxylase-Beta and its Unique Features., Joohun Ha, Jung-Kee Lee, Kyung-Sup Kim, Lee A. Witters, Ki-Han Kim
Dartmouth Scholarship

A Truncated Form of the Pho80 cyclin of Saccharomyces Cerevisiae Induces Expression of a Small Cytosolic Factor which Inhibits Vacuole Inheritance., Teresa Nicolson, Barbara Conradt, William Wickner
Dartmouth Scholarship

A Novel Iron-Regulated Metal Transporter from Plants Identified by Functional Expression in Yeast., David Eide, Margaret Broderius, Jeanette Fett, Mary Lou Guerinot
Dartmouth Scholarship

Circadian Clock Locus Frequency: Protein Encoded by a Single Open Reading Frame Defines Period Length and Temperature Compensation., Benjamin D. Aronson, Keith A. Johnson, Jay C. Dunlap
Dartmouth Scholarship

Binding of Matrix Attachment Regions to Lamin Polymers Involves Single-Stranded Regions and the Minor Groove., M. E. Eva Ludérus, Jan L. den Blaauwen, Oncko J. de Smit, Duane A. Compton, Roel van Driel
Dartmouth Scholarship

The Primary Structure of a Fungal Chitin Deacetylase Reveals the Function for Two Bacterial Gene Products., Dimitris Kafetzopoulos, George Thireos, John N. Vournakis, Vassilis Bouriotis
Dartmouth Scholarship

Modification of Chromium(VI)-Induced DNA Damage by Glutathione and Cytochromes P-450 in Chicken Embryo Hepatocytes., Doreen Y. Cupo, Karen E. Wetterhahn
Dartmouth Scholarship

Spermidine-Condensed Phi X174 DNA Cleavage by Micrococcal Nuclease: Torus Cleavage Model and Evidence for Unidirectional Circumferential DNA Wrapping., Kenneth A. Marx, Thomas C. Reynolds
Dartmouth Scholarship