ENGS 89/90 Reports

Degree Program

B.E.

Project Advisor

Professor Jiwon Lee

Instructor

Professor Douglas W. Van Citters Professor Solomon G. Diamond

Document Type

Report

Publication Date

3-6-2020

Abstract

From pharmaceuticals to biofuels, fermentation bioprocessing has gained traction in many industries reaching a global market value of almost $60 billion in 2018. However, applications of bioprocessing have been limited in scope due to high capital costs, long development times, and difficulties maintaining productivity during scale-up. Furthering development and scale-up of fermentation bioprocesses require careful monitoring and control through analytical chemistry. Currently, there are no small molecule quantification techniques that are sufficiently accurate, inexpensive, and high-throughput. This investigation explores viability of a novel quantification assay for amino acids in fermentation broth leveraging molecularly imprinted polymers (MIPs) and gold nanoparticles (AuNPs).

Level of Access

Restricted: Campus/Dartmouth Community Only Access

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