Infectious Agents and Cancer
Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication (“shedding”) at mucosal sites, especially the oropharynx. Patterns of HHV-8 shedding are not well understood, and require elucidation to better predict risk of HHV-8 related malignancies in those infected. We sought to characterize patterns of HHV-8 oropharyngeal shedding among diverse cohorts that enrolled HHV-8 seropositive persons.
Bender Ignacio, Rachel A.; Goldman, Jason D.; Magaret, Amalia S.; Selke, Stacy; Huang, Meei-Li; Gantt, Soren; Johnston, Christine; Phipps, Warren; Schiffer, Joshua; and Zuckerman, Richard, "Patterns of Human Herpesvirus-8 Oral Shedding among Diverse Cohorts of Human Herpesvirus-8 Seropositive Persons" (2016). Open Dartmouth: Faculty Open Access Articles. 1005.