Journal of Bacteriology
Pseudomonas aeruginosa produces outer membrane vesicles (OMVs) that contain a number of secreted bacterial proteins, including phospholipases, alkaline phosphatase, and the CFTR inhibitory factor (Cif). Previously, Cif, an epoxide hydrolase, was shown to be regulated at the transcriptional level by epoxides, which serve as ligands of the repressor, CifR. Here, we tested whether epoxides have an effect on Cif levels in OMVs. We showed that growth of P. aeruginosa in the presence of specific epoxi
Ballok, A. E.; Filkins, L. M.; Bomberger, J.. M.; Stanton, B. A.; and O'Toole, George A., "Epoxide-Mediated Differential Packaging of Cif and Other Virulence Factors into Outer Membrane Vesicles" (2014). Open Dartmouth: Faculty Open Access Articles. 1039.