Journal of Bacteriology
The 375-bp sarA open reading frame is driven by three promoters, P1, P3, and P2. Using gel shift and DNase I footprinting assays, we found that SarA binds to two 26-bp sequences and one 31-bp sequence within the P1 and P3 promoters, respectively. Together with the results of transcription analyses, our data indicate that SarA binds to its own promoter to down-regulate sarA expression.
Cheung, Ambrose L.; Nishina, Koren; and Manna, Adhar C., "SarA of Staphylococcus aureus Binds to the sarA Promoter To Regulate Gene Expression" (2007). Open Dartmouth: Faculty Open Access Scholarship. 1084.