Journal of Bacteriology
Geisel School of Medicine
SecA undergoes conformational changes during translocation, inserting domains into and across the membrane or enhancing the protease resistance of these domains. We now show that some SecA bound at SecYEG is accessible from the periplasm to a membrane-impermeant probe in cells with a permeabilized outer membrane but an intact plasma membrane.
Eichler J, Wickner W. The SecA subunit of Escherichia coli preprotein translocase is exposed to the periplasm. J Bacteriol. 1998;180(21):5776-5779. doi:10.1128/JB.180.21.5776-5779.1998
Dartmouth Digital Commons Citation
Eichler, Jerry and Wickner, William, "The SecA Subunit of Escherichia coli Preprotein Translocase Is Exposed to the Periplasm" (1998). Dartmouth Scholarship. 1380.