Atypical antipsychotic medications are widely prescribed for the adjunctive treatment of depression, yet their total risk-benefit profile is not well understood. We thus conducted a systematic review of the efficacy and safety profiles of atypical antipsychotic medications used for the adjunctive treatment of depression.
Spielmans, Glen I.; Berman, Margit I.; Linardatos, Eftihia; and Rosenlicht, Nicholas. Z., "Adjunctive Atypical Antipsychotic Treatment for Major Depressive Disorder: A Meta-Analysis of Depression, Quality of Life, and Safety Outcomes" (2013). Open Dartmouth: Faculty Open Access Articles. 1573.