Department of Biological Sciences
Background: Limited data exist on the contribution of dietary sources of arsenic to an individual's total exposure, particularly in populations with exposure via drinking water. Here, the association between diet and toenail arsenic concentrations (a long-term biomarker of exposure) was evaluated for individuals with measured household tap water arsenic. Foods known to be high in arsenic, including rice and seafood, were of particular interest.
Methods: Associations between toenail arsenic and consumption of 120 individual diet items were quantified using general linear models that also accounted for household tap water arsenic and potentially confounding factors (e.g., age, caloric intake, sex, smoking) (n = 852). As part of the analysis, we assessed whether associations between log-transformed toenail arsenic and each diet item differed between subjects with household drinking water arsenic concentrations <1 μg/L versus ≥1 μg/L.
Cottingham KL, Karimi R, Gruber JF, Zens MS, Sayarath V, Folt CL, Punshon T, Morris JS, Karagas MR. Diet and toenail arsenic concentrations in a New Hampshire population with arsenic-containing water. Nutr J. 2013 Nov 16;12:149. doi: 10.1186/1475-2891-12-149. PMID: 24237880; PMCID: PMC3907042.
Dartmouth Digital Commons Citation
Cottingham, Kathryn L.; Karimi, Roxanne; Gruber, Joann F.; Zens, M Scot; Sayarath, Vicki; Folt, Carol L.; Punshon, Tracy; Morris, J. Steven; and Karagas, Margaret R., "Diet and Toenail Arsenic Concentrations in a New Hampshire Population with Arsenic-Containing Water" (2013). Dartmouth Scholarship. 1600.