Journal of Experimental & Clinical Cancer Research
Background: Hepatectomy generally offers the best chance of long-term survival for patients with hepatocellular carcinoma (HCC). Many studies have shown that hepatectomy accelerates tumor metastasis, but the mechanism remains unclear.
Methods: An orthotopic nude mice model with palliative HCC hepatectomy was performed in this study. Metastasis-related genes in tumor following resection were screened; HCC invasion, metastasis, and some molecular alterations were examined in vivo and in vitro. Clinical significance of key gene mRNA expression was also analyzed.
Huang, Xiu-Yan; Huang, Zi-Li; Xu, Bin; and Chen, Zi, "Elevated MTSS1 Expression Associated with Metastasis and Poor Prognosis of Residual Hepatitis B-Related Hepatocellular Carcinoma" (2016). Open Dartmouth: Faculty Open Access Articles. 1675.