Clinical Case Reports
Sodium thiosulfate (STS), first-line treatment for calcific uremic arteriolopathy, causes a mild asymptomatic acidosis in many patients. However, severe, life-threatening acidosis out of proportion with the expected acid load of STS may occur, potentially due to metabolism of STS to hydrogen sulfide.
Hunt, Guenola M. and Ryder, Hilary F., "Metabolic Acidosis after Sodium Thiosulfate Infusion and the Role of Hydrogen Sulfide" (2018). Open Dartmouth: Faculty Open Access Articles. 2844.