Journal of Cellular and Molecular Medicine
Geisel School of Medicine
The extracellular matrix plays a number of important roles, among them providing structural support and information to cellular structures such as blood vessels imbedded within it. As more complex organisms have evolved, the matrix ability to direct signalling towards the vasculature and remodel in response to signalling from the vasculature has assumed progressively greater importance. This review will focus on the molecules of the extracellular matrix, specifically relating to vessel formation and their ability to signal to the surrounding cells to initiate or terminate processes involved in blood vessel formation.
Rhodes JM, Simons M. The extracellular matrix and blood vessel formation: not just a scaffold. J Cell Mol Med. 2007 Mar-Apr;11(2):176-205. doi: 10.1111/j.1582-4934.2007.00031.x. PMID: 17488472; PMCID: PMC3822822.
Dartmouth Digital Commons Citation
Rhodes, John M. and Simons, Michael, "The Extracellular Matrix and Blood Vessel Formation: Not Just a Scaffold" (2007). Dartmouth Scholarship. 3417.