Document Type

Article

Publication Date

8-25-2015

Publication Title

Journal of Biomedical Optics

Department

Thayer School of Engineering

Additional Department

Geisel School of Medicine

Abstract

The use of fluorescence video imaging to guide surgery is rapidly expanding, and improvements in camera readout dynamic range have not matched display capabilities. Logarithmic intensity compression is a fast, single-step mapping technique that can map the useable dynamic range of high-bit fluorescence images onto the typical 8-bit display and potentially be a variable dynamic contrast enhancement tool. We demonstrate a ∼4.6  times improvement in image quality quantified by image entropy and a dynamic range reduction by a factor of ∼380 by the use of log-compression tools in processing in vivo fluorescence images.

DOI

10.1117/1.JBO.20.8.080504

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