Document Type

Article

Publication Date

10-13-2013

Publication Title

Molecular Biology of the Cell

Department

Geisel School of Medicine

Abstract

A rich and ongoing history of cell biology research has defined the major polymer systems of the eukaryotic cytoskeleton. Recent studies have identified additional proteins that form filamentous structures in cells and can self-assemble into linear polymers when purified. This suggests that the eukaryotic cytoskeleton is an even more complex system than previously considered. In this essay, I examine the case for an expanded definition of the eukaryotic cytoskeleton and present a series of challenges for future work in this area.

DOI

10.1091/mbc.E12-10-0732

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