Crystallization of the Staphylococcus Aureus MazF mRNA Interferase
Acta Crystallographica. Section F - Structural Biology and Crystallization Communications
mazEF modules encode toxin–antitoxin pairs that are involved in the bacterial stress response through controlled and specific degradation of mRNA. Staphylococcus aureus MazF and MazE constitute a unique toxin–antitoxin module under regulation of the sigB operon. A MazF-type mRNA interferase is combined with an antitoxin of unknown fold. Crystals of S. aureus MazF (SaMazF) were grown in space group P212121. The crystals diffracted to 2.1 Å resolution and are likely to contain two SaMazF dimers in the asymmetric unit.
Zorzini, Valentina; Haesaerts, Sarah; Donegan, Niles P.; and Fu, Zhibiao, "Crystallization of the Staphylococcus Aureus MazF mRNA Interferase" (2011). Open Dartmouth: Faculty Open Access Articles. 418.