Antimicrobial Agents and Chemotherapy
Surface-associated bacterial communities known as biofilms are an important source of nosocomial infections. Microorganisms such as Pseudomonas aeruginosa can colonize the abiotic surfaces of medical implants, leading to chronic infections that are difficult to eradicate. Our study demonstrates that polysorbate 80 (PS80), a surfactant commonly added to food and medicines, is able to inhibit biofilm formation by P. aeruginosa on a variety of surfaces, including contact lenses.
Toutain-Kidd, C M.; Kadivar, S C.; Bramante, C T.; Bobin, S A.; and Zegans, Michael E., "Polysorbate 80 Inhibition of Pseudomonas aeruginosa Biofilm Formation and Its Cleavage by the Secreted Lipase LipA" (2009). Open Dartmouth: Faculty Open Access Articles. 471.