Arthritis Research and Therapy
In Sjögren's syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular surface. We investigated the effect of blockade of the lymphotoxin-beta receptor (LTBR) pathway on lacrimal-gland pathology in the NOD mouse model of Sjögren's syndrome.
Fava, Roy A.; Kennedy, Susan M.; Wood, Sheryl G.; Bolstad, Anne I.; Bienkowska, Jadwiga; Papandile, Adrian; and Kelly, John A., "Lymphotoxin-Beta Receptor Blockade Reduces CXCL13 in Lacrimal Glands and Improves Corneal Integrity in the NOD Model of Sjögren's Syndrome" (2011). Open Dartmouth: Faculty Open Access Articles. 533.