It is increasingly clear that common human diseases have a complex genetic architecture characterized by both additive and nonadditive genetic effects. The goal of the present study was to determine whether patterns of both additive and nonadditive genetic associations aggregate in specific functional groups as defined by the Gene Ontology (GO).
Dartmouth Digital Commons Citation
Kim, Nora Chung; Andrews, Peter C.; Asselbergs, Folkert W.; Frost, H Robert; Williams, Scott M.; Harris, Brent T.; Read, Cynthia; Askland, Kathleen D.; and Moore, Jason H., "Gene Ontology Analysis of Pairwise Genetic Associations in Two Genome-Wide Studies of Sporadic ALS" (2012). Dartmouth Scholarship. 549.