Document Type
Article
Publication Date
12-21-2007
Publication Title
BioMed Central Genomics
Department
Department of Biological Sciences
Abstract
Genomic research tools such as microarrays are proving to be important resources to study the complex regulation of genes that respond to environmental perturbations. A first generation cDNA microarray was developed for the environmental indicator species Daphnia pulex, to identify genes whose regulation is modulated following exposure to the metal stressor cadmium. Our experiments revealed interesting changes in gene transcription that suggest their biological roles and their potentially toxicological features in responding to this important environmental contaminant.
DOI
10.1186/1471-2164-8-477
Original Citation
Shaw JR, Colbourne JK, Davey JC, Glaholt SP, Hampton TH, Chen CY, Folt CL, Hamilton JW. Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneins. BMC Genomics. 2007 Dec 21;8:477. doi: 10.1186/1471-2164-8-477. PMID: 18154678; PMCID: PMC2234263.
Dartmouth Digital Commons Citation
Shaw, Joseph R.; Colbourne, John K.; Davey, Jennifer C.; Glaholt, Stephen P.; Hampton, Thomas H.; Chen, Celia Y.; Folt, Carol L.; and Hamilton, Joshua W., "Gene Response Profiles for Daphnia Pulex Exposed to the Environmental Stressor Cadmium Reveals Novel Crustacean Metallothioneins" (2007). Dartmouth Scholarship. 606.
https://digitalcommons.dartmouth.edu/facoa/606