BioMed Central Infectious Diseases
Active tuberculosis (TB) is common among HIV-infected persons living in tuberculosis endemic countries, and screening for tuberculosis (TB) is recommended routinely. We sought to determine the role of chest x-ray and sputum culture in the decision to treat for presumptive TB using active case finding in a large cohort of HIV-infected patients. Ambulatory HIV-positive subjects with CD4 counts ≥ 200/mm3 entering a Phase III TB vaccine study in Tanzania were screened for TB with a physical examination, standard interview, CD4 count, chest x-ray (CXR), blood culture for TB, and three sputum samples for acid fast bacillus (AFB) smear and culture.
Bakari, Muhammad; Arbeit, Robert D.; Mtei, Lillian; Lyimo, Johnson; Waddell, Richard; Matee, Mecky; Cole, Bernard F.; and Tvaroha, Susan, "Basis for Treatment of Tuberculosis among HIV-Infected Patients in Tanzania: The Role of Chest X-Ray and Sputum Culture" (2008). Open Dartmouth: Faculty Open Access Articles. 630.