Department of Biological Sciences
In the multinucleate filamentous fungus Ashbya gossypii, nuclei divide asynchronously in a common cytoplasm. We hypothesize that the division cycle machinery has a limited zone of influence in the cytoplasm to promote nuclear autonomy. Mitochondria in cultured mammalian cells undergo cell cycle-specific changes in morphology and membrane potential and therefore can serve as a reporter of the cell cycle state of the cytoplasm. To evaluate if the cell cycle state of nuclei in A. gossypii can influ
Gerstenberger JP, Occhipinti P, Gladfelter AS. Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells. Eukaryot Cell. 2012 Mar;11(3):353-67. doi: 10.1128/EC.05257-11. Epub 2012 Jan 20. PMID: 22267774; PMCID: PMC3294448.
Dartmouth Digital Commons Citation
Gerstenberger, John P.; Occhipinti, Patricia; and Gladfelter, Amy S., "Heterogeneity in Mitochondrial Morphology and Membrane Potential Is Independent of the Nuclear Division Cycle in Multinucleate Fungal Cells" (2012). Dartmouth Scholarship. 819.