Title

Small-Animal Imaging Using Diffuse Fluorescence Tomography.

Document Type

Book Chapter

Publication Date

1-1-2016

Publication Title

Methods in Molecular Biology

Abstract

Diffuse fluorescence tomography (DFT) has been developed to image the spatial distribution of fluorescence-tagged tracers in living tissue. This capability facilitates the recovery of any number of functional parameters, including enzymatic activity, receptor density, blood flow, and gene expression. However, deploying DFT effectively is complex and often requires years of know-how, especially for newer mutlimodal systems that combine DFT with conventional imaging systems. In this chapter, we step through the process of using MRI-DFT imaging of a receptor-targeted tracer in small animals.

DOI

10.1007/978-1-4939-3721-9_12

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