Small-Animal Imaging Using Diffuse Fluorescence Tomography.
Methods in Molecular Biology
Thayer School of Engineering
Diffuse fluorescence tomography (DFT) has been developed to image the spatial distribution of fluorescence-tagged tracers in living tissue. This capability facilitates the recovery of any number of functional parameters, including enzymatic activity, receptor density, blood flow, and gene expression. However, deploying DFT effectively is complex and often requires years of know-how, especially for newer mutlimodal systems that combine DFT with conventional imaging systems. In this chapter, we step through the process of using MRI-DFT imaging of a receptor-targeted tracer in small animals.
Dartmouth Digital Commons Citation
Davis, Scott and Tichauer, Kenneth M., "Small-Animal Imaging Using Diffuse Fluorescence Tomography." (2016). Dartmouth Scholarship. 82.