Document Type

Article

Publication Date

1-2005

Publication Title

Infection and Immunity

Abstract

We investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity against Toxoplasma gondii. IL-17R−/− mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a defect in the migration of polymorphonuclear leukocytes to infected sites during early infection.

DOI

10.1128/IAI.73.1.617-621.2005

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