This section contains dissertations by Dartmouth students. To browse dissertations by subject, go to Academic Departments and look under a specific department or program.

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Theses/Dissertations from 2025

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Ecology of Ixodes scapularis Say: Experimental and Observational Studies with Social Perspectives on Ticks and Tick-Borne Diseases, Kaitlin M. McDonald

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BEHAVIORAL AND NEURAL EFFECTS OF DISTRIBUTING VISUAL ATTENTION ACROSS LOCATION AND FEATURE SPACE, Mert Özkan

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Polarimetric Capture and Differentiable Rendering, Katherine Anne Salesin

Theses/Dissertations from 2024

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Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection., Leena Abdullah

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On Pattern Avoidance and Dynamical Algebraic Combinatorics, Benjamin Adenbaum

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Bridging the Gap Between Molecular Components and Functional Electronic Chemical Sensing Devices with 2D Layered, Conductive Metal–Organic Frameworks, Emma Katherine Ambrogi

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Targeting Cholinergic Signaling in Glioblastoma, Sumyuktha Vijay Anand

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Inflammaging in the Alzheimer’s Brain and Beyond: Insights from a Transgenic Mouse Model on the Sex-specific Pathophysiology of Alzheimer’s Disease, Alicia Jeanne Barber

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Wee1 and Cell Size Control in Fission Yeast by the Protein Kinase Cdr2, Rachel Berg-Murante

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BIOGENESIS AND FUNCTION OF MICROGLIAL EXTRACELLULAR VESICLES IN NEUROINFLAMMATION AND PARKINSON’S DISEASE, Karl E. Biggs

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Social Interactions and Spatial Structure Drive Community Assembly of Bacterial Biofilm, Matthew C. Bond

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MODELS OF LOW MASS STARS AS PHYSICAL LABRATORIES, Emily M. Boudreaux

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ROBUST AND GENERALIZABLE REPRESENTATIONS IN THE HIPPOCAMPUS, Hung-Tu Chen

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CHARACTERIZATION OF ANTIBODY REPERTOIRES DEVELOPED FROM NAIVE AND RECALL RESPONSES, Nicholas C. Curtis

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ADVANCING OMNIMODALITY: EXPANDING HUMAN CREATIVITY THROUGH ADAPTABLE AND ACCESSIBLE MULTIMODAL COMPUTING SYSTEMS, Joshua Urban Davis

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Chromatin regulation by SWI/SNF remodelers in somatic stem cell maintenance and transformation, Luke Thomas Deary

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Development of Novel Radiotherapy Treatment Monitoring and Quantitative Cherenkov Surface Dosimetry for Diverse Populations, Savannah M. Decker

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Mitochondrial Quality Control by Tail-Anchored Proteins, Jose M. Delgado

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Causes and Consequences of Mitotic Chromosome Missegregation in Human Pluripotent Stem Cells, Chenhui Deng

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TOWARD ELECTRICAL IMPEDANCE SENSING SURGICAL DRILL FOR TISSUE BOUNDARY DETECTION, Harshavardhan Devaraj

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Evolution and Adaptation to Temperature in Thermotogota, Anne Amelia Farrell

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Near-Infrared Paired-Agent Imaging for In Vivo Quantification of Receptor Occupancy in Tumor, YICHEN FENG

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On generating bijections for permutations and inversion sequences, Melanie J. Ferreri

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The Influence of Sediment-Supply on River Recovery from Reach to Watershed-Scales, Jordan Fields

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Investigating the mechanisms of surface sensing using motility appendages by Pseudomonas aeruginosa PA14, Christopher James Geiger

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Exploring Group Behavior through Evolutionary Game Theory: Disease Dynamics, Cooperation, and Reputation, Alina Glaubitz

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Leveraging Uncertainty to Understand the Causes and Consequences of Observed Climate Change, Alexander Reid Gottlieb

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Advances in Computational and Statistical Inverse Problems, Dylan Green

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Towards Trustworthy LLMs: Understanding the Security and Privacy Risks of Large Language Models, Kang Gu

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Machine Learning for Graph Algorithms and Representations, Allison Gunby-Mann

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Leveraging Large Language Models for Enhancing Well-being in the Digital Age, Xiaobo Guo

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Targeting Aspergillus fumigatus hypoxia response pathways for novel antifungal drug development., Cecilia Gutierrez Perez

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Liquid Metal Printing of Ultrathin Conductive Metal Oxides, Andrew B. Hamlin

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Formation of new cohesive linkages and regulation of cohesion rejuvenation during meiotic prophase in Drosophila oocytes, Muhammad Abdul Haseeb

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Gaze in Context: Individual and Group Differences in Real-World Visual Attention, Amanda J. Haskins

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Psychophysical and Pharmacological Models of Visual Hallucination, Nathan H. Heller

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Methods, Analyses, and Applications of Multilayer Temporal Link Prediction in Networks, Xie He

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Efficacy and Mechanism of Action of CD40 Ligand and Interleukin-12 Plasmid Electroporation Intratumoral Immunotherapy, Gregory W. Ho

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Scalable Fabrication Methods for Energy Devices, Julia Elizabeth Huddy

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Targeting the Cholesterol Storage Enzyme ACAT1/SOAT1 in Brain Cells and Mouse Model: A Novel Approach to Address Aging and APOE4-Related Neuroinflammation, Thao Nguyen Phuong Huynh Krumeich

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Regulation and therapeutic targeting of virus-specific resident memory T cells, Jordan Fredriksen Isaacs

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Cytokine activity estimation and receptor abundance approximation with multimodal scRNA-seq/CITE-seq data., Azka Javaid

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DEEP LEARNING APPROACHES FOR CANCER PROGNOSIS PREDICTION USING HISTOPATHOLOGICAL, OMICS, AND CLINICAL DATA, Shuai Jiang

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Efficient and Effective Learning of Foundational Large Multi-Modal Models, Yiren Jian

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INTEGRATING HIGHER-ORDER COGNITION WITH SENSORY EXPERIENCE: INSIGHTS FROM CUE-BASED EXPECTATIONS ACROSS DIVERSE DOMAINS, Heejung Jung

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Targeting pyruvate metabolism leads to distinct CD8+ T cell responses to virus infection and cancer, Taewook Kang

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Empowering Vaccine Development: Integrating systems serology, machine learning and antibody engineering to tackle resilient pathogens, Natasha S. Kelkar

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Structure-based targeting of the NEMO:IKK interaction for canonical NF-κB inhibition, Amy Kennedy

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UNDERSTANDING THE NON-CANONICAL REGULATION OF SREBP IN ASPERGILLUS FUMIGATUS, Muhammad Abubakar Khan

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Terrestrial Exchange of Atmospheric Metals: Insights from Fallout Radionuclides, Joshua D. Landis

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Characterization of Stealth Liposome-Based Nanoparticles Encapsulating ACAT1/SOAT1 Inhibitor F26: Potential Therapeutics for Niemann-Pick Type C and Other Neurodegenerative Diseases., Junghoon Lee

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Misery's Company: Modeling the Public and Private Faces of Suicidal Thought and Behavior in the Digital Era, Damien Lekkas

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Towards scalable autonomous underwater construction with free-floating robots, Samuel Eric Lensgraf

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Penney’s game for permutations, Yixin Lin

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Identifying Environmental and Genetic Risk Factors of Diseases in Case-control Studies, Siting Li

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SIMULATING CROSS-SCALE SOLID-FLUID INTERACTION PHENOMENA, Jinyuan Liu

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Aligning Language Models with the Human World, RUIBO LIU

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Germanium-Tin on Silicon for Integrated Photonics and Integrated Quantum Materials, Shang Liu

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GOVERNING DYNAMIC WATERSHEDS UNDER STATIC INSTITUTIONS – EXAMINING HOW LOCAL GOVERNMENTS RESPOND TO FLOODS AND DROUGHTS IN THE UNITED STATES, Jonathon R. Loos

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Target Selection and Enhancement During Attentional Tracking, Marvin R. Maechler

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Khovanov Homology and Legendrian Simple Knots, Ryan J. Maguire

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Mechanistic Insights on Positive Regulation of the Pyrin Inflammasome in Macrophages, Haleema Sadia Malik

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Scalable Methods for Resource-Constrained Adaptive Sampling, Kizito Masaba

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Mitigating Safety Issues in Pre-trained Language Models: A Model-Centric Approach Leveraging Interpretation Methods, Weicheng Ma

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COMPUTATIONAL MODELLING AND DESIGN OF ANTIBODIES: BENEFITS FROM ANALYSIS OF THEIR UNIQUE STRUCTURAL MOTIFS, Katherine M. McCoy

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Consistent Monte Carlo methods for non-linear applications in light transport, Zackary T. Misso

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Driving CARs down memory lane: uncovering CAR memory T cell and antigenspecific endogenous T cells importance in durable responses against melanoma, Asmaa Mohamed

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Patterned Magnetic And Plasmonic Nanostructures In Microfluidics For Extracellular Vesicle Screening And Drug Loading, John H. Molinski

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Novel adaptations in iron regulation acquired during chronic fungal CF infections, Daniel R. Murante

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Sounding the alarm: Local cues that drive functional specialization of brain resident memory T cells, Shawn Christopher Musial Jr.

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Analysis, Optimization, and Design of Small-Scale Hybrid-Core Inductor Designs that Achieve High Energy Densities and Low Loss, Andrew B. Nadler

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Toward the Integration of Behavioral Sensing and Artificial Intelligence, Subigya K. Nepal

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QUANTITATIVE PROTEOMIC STRATEGIES TO DETERMINE SUBSTRATE SPECIFICITIES OF PHOSPHOPROTEIN PHOSPHATASES, Hieu Trung Nguyen

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De novo Synthetic Studies on Tetracyclic Triterpenoid Systems: Stereoselective Preparation, Biological Evaluation and Total Syntheses of Euphol and Tirucallol, Joshua Nicholson

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Role of SDS-22/PP1 phosphatase in polarizing the germplasm of Caenorhabditis elegans embryo, Aparna Nurni Ravi

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HeartFEV1: A MOBILE ELECTROCARDIOGRAM BASED SYSTEM FOR INFERRING FORCED EXPIRATORY VOLUME IN ONE SECOND FROM PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE, Maria Nyamukuru

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The Impacts of Impurities and Stress State on Polycrystalline Ice Deformation and Investigations into the Densification of Polar Firn, Ayobami Oladapo Ogunmolasuyi

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Microglial Dynamics and Mechanisms Underlying the Phagocytosis of Dying Oligodendrocytes, Genaro E. Olveda

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Energy and Empowerment in the High Arctic, Alyssa Pantaleo

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FleQ and Gac/Rsm-Mediated Regulation of Biofilm Formation and Swarming Motility in Pseudomonas fluorescens, Alexander Benito Pastora

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The Large-scale Environments of Active Galactic Nuclei, Grayson C. Petter

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EXPLORING THE ROLES OF PHYSIOLOGY AND PHYLOGENY IN NOVEL SIGNAL EVOLUTION, Mia E. Phillips

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Computational Drug Repositioning and 3D Skin-Like Tissues Identify Anti-Fibrotic Targets for Systemic Sclerosis (SSc), Dillon Popovich

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LEVERAGING PASSIVELY-COLLECTED WEARABLE ACCELEROMETRY DATA COUPLED WITH MACHINE LEARNING TO LONGITUDINALLY DETECT AND PREDICT MAJOR DEPRESSIVE DISORDER, George D. Price

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Exploiting DNA damage repair for the treatment of pediatric tumors that arise in Fanconi anemia, Laura M. Price

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MEASURING SPONTANEOUS NEUROTRANSMISSION USING GENETICALLY ENCODED FLUORESCENT INDICATORS, Amelia Jane Ralowicz

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Investigating the mechanisms for priming and maintaining tumor Ag specific CD8+ T cell responses in the context of CD4-depletion, Delaney E. Ramirez

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Young Atmospheres Spiriting Away, Keighley Elizabeth Rockcliffe

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Estrogen Receptor (ER) Alpha Regulatory Mechanisms and Therapeutic Strategies in ER+ Breast Cancer, Bianca A. Romo

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3-D Reconstruction for Underwater Robots with a Monocular Camera and Lights, Monika Roznere

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Thermal Phase Fluctuations in Narrow Superfluid Rings, Parth Sabharwal

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HETEROGENEITY AND PLASTICITY OF THE NAÏVE CD4+ T CELL COMPARTMENT, Alia Sajani

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BEHAVIORAL AND NEURAL EVIDENCE FOR PERCEPTUAL INFERENCE OF POSITION, Sharif Saleki

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Host-Microbe Interactions and the Developing Gut Microbiome in Infants with Cystic Fibrosis, Paige E. Salerno

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Random Walk Methods for Geometry Representation Agnostic Transport, Dario R. Seyb

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Surgical Navigation in Image-Guided Transoral Robotic Surgery, Yuan Shi

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Regulation and Function of PP2A-B56delta and its Pathological Variants, Kali A. Smolen

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Design, Analysis, and Drop Assembly of Interlocking Rigid Bodies, Amy K. Sniffen

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Studies in Natural Product-Inspired Complex Molecule Synthesis: Synthesis of 26-Norpentacyclic Triterpenoids and Anhydroryanodol, Zachary D. Stempel

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On adaptivity and randomness for streaming algorithms, Manuel Stoeckl