ENGS 89/90 Reports

Year of Graduation

2024

Project Advisor

Scott Davis

Instructor

Solomon Diamond

Document Type

Report

Publication Date

2024

Abstract

Central-line associated bloodstream infections (CLABSI) are a potentially lethal side effect of central-line catheter insertion and use. Currently, there are no targeted approaches to reduce the risk of developing a CLABSI. This project aims to develop a UV-based sterilization system to sterilize incoming catheter fluid. The final design is a single-channel attachment that attaches to a patient catheter port via Luer locks, with UV-LED diodes placed on top of a quartz glass window in the channel to sterilize fluid as it flows through the device. This report describes four primary technical objectives, including measuring the radiation achieved by UV-LED diodes, developing a 3D-printed prototype of the device, measuring the bactericidal properties of the combined UV-LED and channel design, and measuring the effect of the channel on incoming fluid flow. Based on the experimental results, we identified a potentially feasible device design that met the UV radiation and fluid flow requirements. The device was found to be bactericidal at low clinical flow rates, but efficacy dropped as flow rates increased. Additionally, the temperature of the diode was found to increase rapidly while powered. Future work should address the issue of heat emitted by the diode as well as potential redesigning of the circuit board used to power the diodes.

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