Document Type

Article

Publication Date

6-22-2016

Publication Title

Journal of Bacteriology

Department

Geisel School of Medicine

Abstract

We previously identified a second-messenger-regulated signaling system in the environmental bacterium Pseudomonas fluorescens which controls biofilm formation in response to levels of environmental inorganic phosphate. This system contains the transmembrane cyclic di-GMP (c-di-GMP) receptor LapD and the periplasmic protease LapG. LapD regulates LapG and controls the ability of this protease to process a large cell surface adhesin protein, LapA. While LapDG orthologs can be identified in diverse

DOI

10.1128/JB.00369-15

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