Document Type
Article
Publication Date
2-5-2015
Publication Title
Respiratory Research
Department
Geisel School of Medicine
Abstract
Influenza is a common respiratory virus and Staphylococcus aureus frequently causes secondary pneumonia during influenza infection, leading to increased morbidity and mortality. Influenza has been found to attenuate subsequent Type 17 immunity, enhancing susceptibility to secondary bacterial infections. IL-27 is known to inhibit Type 17 immunity, suggesting a potential critical role for IL-27 in viral and bacterial co-infection.
DOI
10.1186/s12931-015-0168-8
Dartmouth Digital Commons Citation
Robinson, Keven M.; Lee, Benjamin; Scheller, Erich V; Mandalapu, Sivanarayana; and Enelow, Richard I., "The Role of IL-27 in Susceptibility to Post-Influenza Staphylococcus Aureus Pneumonia" (2015). Dartmouth Scholarship. 1317.
https://digitalcommons.dartmouth.edu/facoa/1317
