Document Type

Article

Publication Date

11-1998

Publication Title

Journal of Bacteriology

Department

Geisel School of Medicine

Abstract

SecA undergoes conformational changes during translocation, inserting domains into and across the membrane or enhancing the protease resistance of these domains. We now show that some SecA bound at SecYEG is accessible from the periplasm to a membrane-impermeant probe in cells with a permeabilized outer membrane but an intact plasma membrane.

Original Citation

Eichler J, Wickner W. The SecA subunit of Escherichia coli preprotein translocase is exposed to the periplasm. J Bacteriol. 1998;180(21):5776-5779. doi:10.1128/JB.180.21.5776-5779.1998

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