A dynamical model of the transport of asbestos fibres in the human body

Document Type

Article

Publication Date

8-3-2017

Publication Title

Journal of Biological Dynamics

Department

Department of Mathematics

Abstract

We present a model for the transport of a single type of asbestos fibre through the human body. The model captures the transport modes that pertain particularly to the lungs and the mesothelium. Numerical solutions of the system follow observed movement in the body. We compare the accumulation of fibres in the lungs versus the mesothelium, and then we give analysis and results for various cases of exposure level and exposure time. Models, such as the one developed here, can give clues as to how asbestos fibres impact the body, and where to look for major impact.

DOI

10.1080/17513758.2017.1355489

Original Citation

DeStefano A, Martin CF, Wallace DI. A dynamical model of the transport of asbestos fibres in the human body. J Biol Dyn. 2017 Dec;11(1):365-377. doi: 10.1080/17513758.2017.1355489. PMID: 28770658.

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