Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients

Authors

Shama D. Ahuja, Bureau of Tuberculosis
David Ashkin, A.G. Holley Hospital
Monika Avendano, University of Toronto
Rita Banerjee, Mayo Clinic
Melissa Bauer, McGill University
Jamie N. Bayona, Dartmouth CollegeFollow

Document Type

Article

Publication Date

8-2012

Publication Title

PLoS Medicine

Abstract

Dick Menzies and colleagues report findings from a collaborative, individual patient-level meta-analysis of treatment outcomes among patients with multidrug-resistant tuberculosis.

Background: Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB.

DOI

10.1371/annotation/230240bc-bcf3-46b2-9b

Dartmouth Digital Commons Citation

Shama D. Ahuja; Ashkin, David; Avendano, Monika; Banerjee, Rita; Bauer, Melissa; and Bayona, Jamie N., "Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients" (2012). Dartmouth Scholarship. 1555.
https://digitalcommons.dartmouth.edu/facoa/1555