Document Type
Article
Publication Date
7-10-2014
Publication Title
Malaria Journal
Department
Department of Mathematics
Additional Department
Department of Geography
Abstract
Background: Models for malaria transmission are usually compared based on the quantities tracked, the form taken by each term in the equations, and the qualitative properties of the systems at equilibrium. Here five models are compared in detail in order to develop a set of performance measures that further illuminate the differences among models.
Methods: Five models of malaria transmission are compared. Parameters are adjusted to correspond to similar biological quantities across models. Nine choices of parameter sets/initial conditions are tested for all five models. The relationship between malaria incidence in humans and (1) malaria incidence in vectors, (2) man-biting rate, and (3) entomological inoculation rate (EIR) at equilibrium is tested for all models. A sensitivity analysis for all models is conducted at all parameter sets. Overall sensitivities are ranked for each of the five models. A set of simple control interventions is tested on two of the models.
DOI
10.1186/1475-2875-13-268
Dartmouth Digital Commons Citation
Wallace, Dorothy I.; Southworth, Ben S.; Shi, Xun; Chipman, Jonathan W.; and Githeko, Andrew K., "A Comparison of Five Malaria Transmission Models: Benchmark Tests and Implications for Disease Control" (2014). Dartmouth Scholarship. 1621.
https://digitalcommons.dartmouth.edu/facoa/1621
Included in
Applied Mathematics Commons, Epidemiology Commons, International Public Health Commons, Parasitic Diseases Commons