Document Type
Article
Publication Date
12-10-2015
Publication Title
PLoS Neglected Tropical Diseases
Department
Geisel School of Medicine
Abstract
Background: Hypoxic microenvironments are generated during fungal infection. It has been described that to survive in the human host, fungi must also tolerate and overcome in vivo microenvironmental stress conditions including low oxygen tension; however nothing is known how Paracoccidioides species respond to hypoxia. The genus Paracoccidioides comprises human thermal dimorphic fungi and are causative agents of paracoccidioidomycosis (PCM), an important mycosis in Latin America.
DOI
10.1371/journal.pntd.0004282
Dartmouth Digital Commons Citation
Lima, Patrícia de Sousa; Chung, Dawoon; Bailão, Alexandre Melo; Cramer, Robert A.; and Soares, Célia Maria de Almeida, "Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus" (2015). Dartmouth Scholarship. 1666.
https://digitalcommons.dartmouth.edu/facoa/1666