Document Type

Article

Publication Date

5-1-2007

Publication Title

Journal of Cellular and Molecular Medicine

Department

Geisel School of Medicine

Abstract

The extracellular matrix plays a number of important roles, among them providing structural support and information to cellular structures such as blood vessels imbedded within it. As more complex organisms have evolved, the matrix ability to direct signalling towards the vasculature and remodel in response to signalling from the vasculature has assumed progressively greater importance. This review will focus on the molecules of the extracellular matrix, specifically relating to vessel formation and their ability to signal to the surrounding cells to initiate or terminate processes involved in blood vessel formation.

DOI

10.1111/j.1582-4934.2007.00031.x

Original Citation

Rhodes JM, Simons M. The extracellular matrix and blood vessel formation: not just a scaffold. J Cell Mol Med. 2007 Mar-Apr;11(2):176-205. doi: 10.1111/j.1582-4934.2007.00031.x. PMID: 17488472; PMCID: PMC3822822.

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