In Vivo Bioluminescence Imaging To Evaluate Systemic and Topical Antibiotics against Community-Acquired Methicillin-Resistant Staphylococcus aureus-Infected Skin Wounds in Mice

Authors

Yi Guo, University of California, Los Angeles
Romela Irene Ramos, University of California, Los Angeles
John S. Cho, University of California, Los Angeles
Niles P. Donegan, Dartmouth CollegeFollow
Ambrose L. Cheung, Dartmouth CollegeFollow
Lloyd S. Miller, Johns Hopkins University

Document Type

Article

Publication Date

12-3-2013

Publication Title

Antimicrobial Agents and Chemotherapy

Department

Geisel School of Medicine

Abstract

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) frequently causes skin and soft tissue infections, including impetigo, cellulitis, folliculitis, and infected wounds and ulcers. Uncomplicated CA-MRSA skin infections are typically managed in an outpatient setting with oral and topical antibiotics and/or incision and drainage, whereas complicated skin infections often require hospitalization, intravenous antibiotics, and sometimes surgery. The aim of this study was to devel

DOI

10.1128/AAC.01003-12

Dartmouth Digital Commons Citation

Guo, Yi; Ramos, Romela Irene; Cho, John S.; Donegan, Niles P.; Cheung, Ambrose L.; and Miller, Lloyd S., "In Vivo Bioluminescence Imaging To Evaluate Systemic and Topical Antibiotics against Community-Acquired Methicillin-Resistant Staphylococcus aureus-Infected Skin Wounds in Mice" (2013). Dartmouth Scholarship. 469.
https://digitalcommons.dartmouth.edu/facoa/469