Document Type
Article
Publication Date
2010
Publication Title
ARKIVOC - Online Journal of Organic Chemistry
Department
Department of Chemistry
Abstract
1,2-Bis(phenylsulfonyl)-1H-indole is a novel example of an electron-deficient indole that undergoes nucleophilic attack at C-3. Though a variety of other organometallic nucleophiles fail to engender nucleophilic substitution, organocuprates produce 3-substituted 2-(phenylsulfonyl)-1H-indoles. These reactions contribute to the growing number of examples of nucleophilic addition to the indole core.
Dartmouth Digital Commons Citation
Qian, David C.; Alford, Philip E.; Kishbaugh, Tara L. S.; Jones, Sean T.; and Gribble, Gordon W., "1, 2-Bis (phenylsulfonyl)-1H-Indole as an Acceptor of Organocuprate Nucleophiles" (2010). Dartmouth Scholarship. 504.
https://digitalcommons.dartmouth.edu/facoa/504