Gene Ontology Analysis of Pairwise Genetic Associations in Two Genome-Wide Studies of Sporadic ALS

Authors

Nora Chung Kim, Dartmouth College
Peter C. Andrews, Dartmouth CollegeFollow
Folkert W. Asselbergs, University Medical Center of UtrechtFollow
H Robert Frost, Dartmouth CollegeFollow
Scott M. Williams, Dartmouth College
Brent T. Harris, Georgetown University
Cynthia Read, Brown University
Kathleen D. Askland, Brown University
Jason H. Moore, Dartmouth College

Document Type

Article

Publication Date

7-28-2012

Publication Title

BioData Mining

Abstract

It is increasingly clear that common human diseases have a complex genetic architecture characterized by both additive and nonadditive genetic effects. The goal of the present study was to determine whether patterns of both additive and nonadditive genetic associations aggregate in specific functional groups as defined by the Gene Ontology (GO).

DOI

10.1186/1756-0381-5-9

Dartmouth Digital Commons Citation

Kim, Nora Chung; Andrews, Peter C.; Asselbergs, Folkert W.; Frost, H Robert; Williams, Scott M.; Harris, Brent T.; Read, Cynthia; Askland, Kathleen D.; and Moore, Jason H., "Gene Ontology Analysis of Pairwise Genetic Associations in Two Genome-Wide Studies of Sporadic ALS" (2012). Dartmouth Scholarship. 549.
https://digitalcommons.dartmouth.edu/facoa/549