Document Type

Article

Publication Date

12-21-2007

Publication Title

BioMed Central Genomics

Department

Department of Biological Sciences

Abstract

Genomic research tools such as microarrays are proving to be important resources to study the complex regulation of genes that respond to environmental perturbations. A first generation cDNA microarray was developed for the environmental indicator species Daphnia pulex, to identify genes whose regulation is modulated following exposure to the metal stressor cadmium. Our experiments revealed interesting changes in gene transcription that suggest their biological roles and their potentially toxicological features in responding to this important environmental contaminant.

DOI

10.1186/1471-2164-8-477

Original Citation

Shaw JR, Colbourne JK, Davey JC, Glaholt SP, Hampton TH, Chen CY, Folt CL, Hamilton JW. Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneins. BMC Genomics. 2007 Dec 21;8:477. doi: 10.1186/1471-2164-8-477. PMID: 18154678; PMCID: PMC2234263.

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