Completeness of Main Outcomes Across Randomized Trials in Entire Discipline: Survey of Chronic Lung Disease Outcomes in Preterm Infants

John P. A. Ioannidis, Stanford University
Jeffrey D. Horbar, University of Vermont
Colleen M. Ovelman, Neonatal Review Group
Yolanda Brosseau, Neonatal Review Group

Abstract

Objective: To map the availability of information on a major clinical outcome—chronic lung disease—across the randomized controlled trials in systematic reviews of an entire specialty, specifically interventions in preterm infants.