Document Type

Article

Publication Date

1-20-2012

Publication Title

Eukaryotic Cell

Department

Department of Biological Sciences

Abstract

In the multinucleate filamentous fungus Ashbya gossypii, nuclei divide asynchronously in a common cytoplasm. We hypothesize that the division cycle machinery has a limited zone of influence in the cytoplasm to promote nuclear autonomy. Mitochondria in cultured mammalian cells undergo cell cycle-specific changes in morphology and membrane potential and therefore can serve as a reporter of the cell cycle state of the cytoplasm. To evaluate if the cell cycle state of nuclei in A. gossypii can influ

DOI

10.1128/EC.05257-11

Original Citation

Gerstenberger JP, Occhipinti P, Gladfelter AS. Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells. Eukaryot Cell. 2012 Mar;11(3):353-67. doi: 10.1128/EC.05257-11. Epub 2012 Jan 20. PMID: 22267774; PMCID: PMC3294448.

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