Pre- treatment protoporphyrin IX concentration in actinic keratosis lesions predicts response to aminolevulinic-acid based photodynamic therapy
Document Type
Conference Proceeding
Publication Date
9-1-2015
Publication Title
SPIE/NIH
Department
Thayer School of Engineering
Abstract
Although Aminolevulinic Acid (ALA)-induced protoporphyrin IX (PpIX) photodynamic therapy (PDT) is an effective FDA-approved therapy for actinic keratosis (AK), a substantial fraction of patients (up to 25%) do not respond to treatment. This study examined the feasibility of using pre-treatment measurements of PpIX concentration in AK lesions to predict response of ALA-PpIX PDT.
DOI
10.1016/j.pdpdt.2015.10.006
Dartmouth Digital Commons Citation
Kanick, Stephen; Davis, Scott; Zhao, Yan; Hasan, Tayyaba; and Maytin, Edward, "Pre- treatment protoporphyrin IX concentration in actinic keratosis lesions predicts response to aminolevulinic-acid based photodynamic therapy" (2015). Dartmouth Scholarship. 90.
https://digitalcommons.dartmouth.edu/facoa/90
