Tissue-Engineered Delivery of Manuka Honey

Authors

Calista Adler, Dartmouth CollegeFollow
Karina Mitchell, Dartmouth CollegeFollow
Sreejith Panicker, Dartmouth CollegeFollow
Katherine R. Hixon, Dartmouth CollegeFollow

Files

Student Class

2026

Student Affiliation

WISP Intern

First Advisor

Katherine Hixon

First Advisor Department

Department of Engineering Sciences—Thayer School of Engineering

Second Advisor

Sreejith Panicker

Second Advisor Department

Department of Engineering Sciences—Thayer School of Engineering

Description

Manuka Honey (MH) contains the Unique Manuka Honey Factor (UMF), which is directly correlated to honey’s antibacterial efficiency and has a wide range of wound healing properties. In more recent years, MH has been incorporated into tissue-engineering scaffolds including cryogels, hydrogels, electrospun fibers, and electrosprayed nanoparticles. Tissue-engineered scaffolds can serve as alternative vehicles for delivery as compared to traditional wound dressings.The project objective was to investigate which of the four scaffold types can successfully incorporate MH (0, 1, 5, 10%) while retaining original parameters. We hypothesize that cryogels offer the best vehicle of delivery of MH because of increased durability (mechanical properties) compared to that of hydrogels and electrospun/electrosprayed scaffolds.

Publication Date

2023

Keywords

Manuka honey, scaffold, cryogel, hydrogel, electrospinning, electrospraying, SEM

Disciplines

Biomedical Engineering and Bioengineering | Molecular, Cellular, and Tissue Engineering

Dartmouth Digital Commons Citation

Adler, Calista; Mitchell, Karina; Panicker, Sreejith; and Hixon, Katherine R., "Tissue-Engineered Delivery of Manuka Honey" (2023). Wetterhahn Science Symposium Posters 2023. 3.
https://digitalcommons.dartmouth.edu/wetterhahn_2023/3