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Theses/Dissertations from 2025

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Cell Competition Eliminates Aneuploid Human Pluripotent Stem Cells, Amanda I. Ya

Theses/Dissertations from 2024

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Wee1 and Cell Size Control in Fission Yeast by the Protein Kinase Cdr2, Rachel Berg-Murante

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Mitochondrial Quality Control by Tail-Anchored Proteins, Jose M. Delgado

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Causes and Consequences of Mitotic Chromosome Missegregation in Human Pluripotent Stem Cells, Chenhui Deng

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Targeting the Cholesterol Storage Enzyme ACAT1/SOAT1 in Brain Cells and Mouse Model: A Novel Approach to Address Aging and APOE4-Related Neuroinflammation, Thao Nguyen Phuong Huynh Krumeich

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Structure-based targeting of the NEMO:IKK interaction for canonical NF-κB inhibition, Amy Kennedy

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UNDERSTANDING THE NON-CANONICAL REGULATION OF SREBP IN ASPERGILLUS FUMIGATUS, Muhammad Abubakar Khan

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Characterization of Stealth Liposome-Based Nanoparticles Encapsulating ACAT1/SOAT1 Inhibitor F26: Potential Therapeutics for Niemann-Pick Type C and Other Neurodegenerative Diseases., Junghoon Lee

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QUANTITATIVE PROTEOMIC STRATEGIES TO DETERMINE SUBSTRATE SPECIFICITIES OF PHOSPHOPROTEIN PHOSPHATASES, Hieu Trung Nguyen

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Regulation and Function of PP2A-B56delta and its Pathological Variants, Kali A. Smolen

Theses/Dissertations from 2023

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Novel mechanistic insight into ciliary regulation: old pathways yield new mechanisms, Larissa L. Dougherty

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Inhibition of CAL PDZ domain via non-canonical and allosteric interactions reveals new targeting sites and strategies, Nicholas Paul Gill

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The Molecular and Cellular Response to ACAT1/SOAT1 Inhibition, Taylor C. Harned

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PROTEOMIC APPROACHES TO IDENTIFY UNIQUE AND SHARED SUBSTRATES AMONG KINASE FAMILY MEMBERS, Charles Lincoln Howarth

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MITOCHONDRIAL DIVISION: SYNERGIZING IN MITOCHONDRIAL DIVISOME, Ao Liu

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Measuring how kinetochore-microtubule detachment contributes to chromosome movement and the correction of attachment errors, Melissa K. Parks

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Molecular Mechanisms Regulating Prometaphase and Metaphase States for Faithful Chromosome Segregation, Sarah Yvette Valles

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Molecular Mechanisms of Wild-type and Mutant Prion Formation, Daniel J. Walsh

Theses/Dissertations from 2022

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Novel functions for Arp2/3 complex-mediated actin networks discovered in Chlamydomonas reinhardtii, Brae M. Bigge

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DECIPHERING PHOSPHOPROTEIN PHOSPHATASE SIGNALING NETWORKS USING PROTEOMICS APPROACHES, Brooke Brauer

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MECHANISMS AND ROLES OF DYNAMIC ACTIN ASSEMBLY AROUND DYSFUNCTIONAL MITOCHONDRIA, Tak Shun Fung

Theses/Dissertations from 2021

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Bioenergy and Minigrids for Sustainable Human Development, Andrew Allee

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DISCRETIZED GEOMETRIC APPROACHES TO THE ANALYSIS OF PROTEIN STRUCTURES, John Holland