This collection contains works by faculty from the Dartmouth Department of Chemistry.

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Submissions from 2021

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Stimuli-responsive temporary adhesives: Enabling debonding on demand through strategic molecular design, Nicholas D. Blelloch, Hana J. Yarbrough, and Katherine A. Mirica

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Nontargeted screening using gas chromatography– atmospheric pressure ionization mass spectrometry: Recent trends and emerging potential, Xiaolei Li, Frank L. Dorman, Paul A. Helm, Sonya Kleywegt, André Simpson, Myrna J. Simpson, and Karl J. Jobst

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Structure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons, Charles R. Midgett, Kacey Marie Talbot, Jessica L. Day, George P. Munson, and F. Jon Kull

Submissions from 2018

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Solution and Solid-State Emission Toggling of a Photochromic Hydrazone, Baihao Shao, Massimo Baroncini, Laura Bussotti, Mariangela Di Donato, Alberto Credi, and Ivan Aprahamian

Submissions from 2017

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Fluorocarbene, Fluoroolefin, and Fluorocarbyne Complexes of Rh, Christopher Pell, Yanjun Zhu, Rafael Huacuja, David Herbert, Russell Hughes, and Oleg Ozerov

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A New Class of Inhibitors of the AraC Family Virulence Regulator Vibrio Cholerae ToxT, Anne K. Woodbrey, Evans O. Onyango, Maria Pellegrini, Gabriela Kovacikova, Ronald Taylor, Gordon Gribble, and F. Jon Kull

Submissions from 2016

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Synthetic Small Molecule GLP-1 Secretagogues Prepared by Means of a Three-component Indole Annulation Strategy, Oleg G. Chepurny, Colin A. Leech, Martin Tomanik, Maria C. DiPoto, Hui Li, Xinping Han, Qinghe Meng, Robert N. Cooney, Jimmy Wu, and George G. Holz

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Vapor Deposited Cr-doped ZnS Thin Films: Towards Optically Pumped Mid-Infrared Waveguide Lasers, Eric A. Karhu, Charles R. Ildstad, Stefano Poggio, Vedran Furtula, Nikolai Tolstik, Irina T. Sorokina, Joseph J. Belbruno, and Ursula J. Gibson

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The 40-Residue Insertion in Vibrio Cholerae FadR Facilitates Binding of an Additional Fatty acyl-CoA Ligand, Wei Shi, Gabriela Kovacikova, Wei Lin, Ronald. K. Taylor, Karen Skorupski, and F. Jon Kull

Submissions from 2015

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A Novel Caspase 8 Selective Small Molecule Potentiates TRAIL-Induced Cell Death, Octavian Bucur, Gabriel Gaidos, Achani Yatawara, Bodvael Pennarun, Chamila Rupasinghe, Jérémie Roux, Stefan Andrei, Bingqian Guo, Alexandra Panaitiu, Maria Pellegrini, Dale Mierke, and Roya Khosravi-Far

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Identification and Characterization of the Interaction Site between cFLIPL and Calmodulin, Gabriel Gaidos, Alexandra E. Panaitiu, Bingqian Guo, Maria Pellegrini, and Dale F. Mierke

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Biological Activity of Recently Discovered Halogenated Marine Natural Products, Gordon Gribble

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Synthesis, Crystal Structures, and DFT Calculations of Three New Cyano(phenylsulfonyl)indoles and a Key Synthetic Precursor Compound, William Montgomery, Justin Lopchuk, Gordon Gribble, and Jerry Jasinski

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Tumor Cell Targeting by Iron Oxide Nanoparticles is Dominated by Different Factors In Vitro versus In Vivo, Christian NDong, Jennifer A. Tate, Warren C. Kett, Jaya Batra, Eugene Demidenko, Lionel D. Lewis, P. Jack Hoopes, Tillmann U. Gerngross, and Karl E. Griswold

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Antibody-Mediated Targeting of Iron Oxide Nanoparticles to the Folate Receptor Alpha Increases Tumor Cell Association In Vitro and In Vivo, Christian Ndong, Seiko Toraya-Brown, Katsiaryna Kekalo, Ian Baker, Tillman U. Gerngross, Steven N. Fiering, and Karl E. Griswold

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(3+2)-Cycloaddition Reactions of Oxyallyl Cations, Jimmy Wu and Hui Li

Submissions from 2014

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Regulating Signal Enhancement with Coordination-Coupled Deprotonation of a Hydrazone Switch, Justin T. Foy, Debdas Ray, and Ivan Aprahamian

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Methyl 1-benzyl-5-methyl-2,4-diphenyl-1H-pyrrole-3-carboxyl-ate, Justin M. Lopchuk, Gordon W. Gribble, and Jerry P. Jasinski

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Redox-Dependent Stability, Protonation, and Reactivity of Cysteine-Bound Heme Proteins, Fangfang Zhong, George P. Lisi, Daniel P. Collins, John H. Dawson, and Ekaterina V. Pletneva

Submissions from 2013

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A Cell Permeable Peptide Targeting the Intracellular Loop 2 of Endothelin B Receptor Reduces Pulmonary Hypertension in a Hypoxic Rat Model, Daniel S. Green, Chamila Rupasinghe, Rod Warburton, Jamie L. Wilson, Christine O. Sallum, Linda Taylor, Achan Yatawara, Dale Mierke, Peter Polgar, and Nicholas Hill

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Bruceolline D: 3,3-dimethyl-1H,4H-cyclo­penta­[b]indol-2(3H)-one, Gordon Gribble, J M. Lopchuck, and J P. Jasinski

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Force Generation by Kinesin and Myosin Cytoskeletal Motor Proteins, F. Jon Kull and Sharyn A. Endow

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KillerFLIP: A Novel Lytic Peptide Specifically Inducing Cancer Cell Death, B Pennarun, G. Gaidos, O Bucur, and A Tinari

Submissions from 2012

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Conformational Properties of Cardiolipin-Bound Cytochrome C, Jonas Hanske, Jason R. Toffey, Anna M. Morenz, Amber J. Bonilla, Katherine H. Schiavoni;, and Ekaterina V. Pletneva

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3,3-Dimethyl-1,2,3,4-tetra­hydro­cyclo­penta­[b]indole-1,2-dione (bruceolline E), Jason A. Jordon, Jeanese C. Badenock, Gordon W. Gribble, Jerry P. Jasinski, and James A. Golen

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The Importance of the Rotor in Hydrazone-Based Molecular Switches, Xin Su, Timo Lessing, and Ivan Aprahamian

Submissions from 2010

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4-Phenyl­sulfon­yl-2-(p-tolyl­sulfon­yl)-1H,8H-pyrrolo­[2,3-b]indole, Jeanese C. Badenock, Jason A. Jordan, Erin T. Pelkey, Gordon W. Gribble, and Jerry P. Jasinski

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A Kinesin Motor in a Force-Producing Conformation, Elisabeth Heuston, C. Eric Bronner, F Jon Kull, and Sharyn A. Endow

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Structure of Vibrio Cholerae ToxT Reveals a Mechanism for Fatty Acid Regulation of Virulence Genes, Michael J. Lowden, Karen Skorupski, Maria Pellegrini, Michael G. Chiorazzo, Ronald K. Taylor, and F. Jon Kull

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1, 2-Bis (phenylsulfonyl)-1H-Indole as an Acceptor of Organocuprate Nucleophiles, David C. Qian, Philip E. Alford, Tara L. S. Kishbaugh, Sean T. Jones, and Gordon W. Gribble

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An Improved Synthesis of a Ring-C Precursor to Cobyric Acid, Hui Wang and Peter A. Jacobi

Submissions from 2009

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Pathogenic Adaptation of Intracellular Bacteria by Rewiring a Cis-Regulatory Input Function, Suzanne E. Osborne, Don Walthers, Ana M. Tomljenovic, David T. Mulder, Uma Silphaduang, Nancy Duong, and Michael J. Lowden

Submissions from 2007

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Crystal Structure of the Vibrio cholerae Quorum-Sensing Regulatory Protein HapR, Rukman S. De Silva, Gabriela Kovacikova, Wei Lin, Ronald K. Taylor, Karen Skorupski, and F. Jon Kull

Submissions from 2006

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Dictyostelium Myosin-IE Is a Fast Molecular Motor Involved in Phagocytosis, Ulrike Durrwang, Setsuko Fujita-Becker, Muriel Erent, and F. Jon Kull

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Reproduction, Embryonic Development, and Maternal Transfer of Contaminants in the Amphibian Gastrophryne Carolinensis, William Alexander Hopkins, Sarah Elizabeth DuRant, Brandon Patrick Staub, Christopher Lee Rowe, and Brian Phillip Jackson

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Modeling the Pinning of Au and Ni Clusters on Graphite, R. Smith, C. Nock, S. D. Kenny, and Joseph J. Belbruno

Submissions from 2005

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Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein–ligand interactions including a structural basis for observed antifolate resistance, Amy C. Anderson

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Synthetic Studies in Phytochrome Chemistry, Peter A. Jacobi, Imad Odeh, Subhas Buddhu, Guolin Cai, Sundaramoorthi Rajeswari, Douglas Fry, Wanjun Zheng, Robert W. DeSimone, Jiasheng Guo, Lisa D. Coutts, Sheila I. Hauck, Sam H. Leung, Indranath Ghosh, and Douglas Pippin

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Crystal Structure of the GTPase Domain of Rat Dynamin 1, Thomas F. Reubold, Susanne Eschenburg, Andreas Becker, Marilyn Leonard, Sandra L. Schmid, Richard B. Vallee, F. Jon Kull, and Dietmar J. Manstein

Submissions from 2004

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Gold Adatoms and Dimers on Relaxed Graphite Surfaces, Guan Ming Wang, Joseph J. BelBruno, Steven D. Kenny, and Roger Smith

Submissions from 2003

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Synthesis of Novel [3, 2-b] Indole Fused Oleanolic Acids as Potential Inhibitors of Cell Proliferation, Heather J. Finlay, Tadashi Honda, and Gordon W. Gribble

Submissions from 2002

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The Anti-Inflammatory Triterpenoid Methyl 2-Cyano-3,12-Dioxooleana-1,9(11)-Dien-28-Oate Methanol Solvate Hydrate, Lothar Bore, Tadashi Honda, Gordon W. Gribble, Enno Lork, and Jerry P. Jasinski

Submissions from 2000

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Reducing Mass Degeneracy in SAR by MS by Stable Isotopic Labeling, Chris Bailey-Kellogg, John J. Kelley III, Cliff Stein, and Bruce Randall Donald

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The NOESY Jigsaw: Automated Protein Secondary Structure and Main-Chain Assignment from Sparse, Unassigned NMR Data, Chris Bailey-Kellogg, Alik Widge, John J. Kelley III, Marcelo J. Berardi, John H. Bushweller, and Bruce Randall Donald

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The Fused Heterocycle 2-Benzyl-3-Methyl-1-Phenyl-4-Phenylsulfonyl-2H,4H-Pyrrolo[3,4-b]Indole, Wendy M. Simon, Hernando A. A. Trujillo, Erin T. Pelkey, Gordon W. Gribble, and Jerry P. Jasinski

Submissions from 1994

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Chromium(VI) Reduction by Ascorbate: Role of Reactive Intermediates in DNA Damage In Vitro, D M. Stearns, K D. Courtney, P H. Giangrande, L S. Phieffer, and Karen E. Wetterhahn

Submissions from 1991

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Multiphoton Ionization of Nitrobenzene in Non-Aqueous Solutions: Characterization of the Cation and Ion-Molecule Chemistry, G. Siuzdak and J. J. Belbruno

Submissions from 1989

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Uv Multiphoton Induced Chemistry of Nitrobenzene in Solution, Joseph J. Belbruno, Gary Siuzdak, and Simon North

Submissions from 1985

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Modification of Chromium(VI)-Induced DNA Damage by Glutathione and Cytochromes P-450 in Chicken Embryo Hepatocytes., Doreen Y. Cupo and Karen E. Wetterhahn

Submissions from 1983

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Evidence for Hydrated Spermidine-Calf Thymus DNA Toruses Organized by Circumferential DNA Wrapping, Kenneth A. Marx and George C. Ruben

Submissions from 1982

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Spermidine-Condensed Phi X174 DNA Cleavage by Micrococcal Nuclease: Torus Cleavage Model and Evidence for Unidirectional Circumferential DNA Wrapping., Kenneth A. Marx and Thomas C. Reynolds

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Excluded-Volume Effect on Quasi-Elastic Light Scattering by Flexible Macromolecules, Genzo Tanaka and Walter H. Stockmayer