Amino Acid Quantification for DMC Biotechnologies

Authors

Russell BeckermanFollow
Rebecca HinesFollow
Kenya JacobFollow
Megan McCabeFollow
Ju Yun LeeFollow

Degree Program

B.E.

Sponsor

DMC Biotechnologies Boulder, Colorado

Project Advisor

Professor Jiwon Lee

Instructor

Professor Douglas W. Van Citters Professor Solomon G. Diamond

Document Type

Report

Publication Date

3-6-2020

Abstract

From pharmaceuticals to biofuels, fermentation bioprocessing has gained traction in many industries reaching a global market value of almost $60 billion in 2018. However, applications of bioprocessing have been limited in scope due to high capital costs, long development times, and difficulties maintaining productivity during scale-up. Furthering development and scale-up of fermentation bioprocesses require careful monitoring and control through analytical chemistry. Currently, there are no small molecule quantification techniques that are sufficiently accurate, inexpensive, and high-throughput. This investigation explores viability of a novel quantification assay for amino acids in fermentation broth leveraging molecularly imprinted polymers (MIPs) and gold nanoparticles (AuNPs).

Level of Access

Restricted: Campus/Dartmouth Community Only Access

Dartmouth Digital Commons Citation

Beckerman, Russell; Hines, Rebecca; Jacob, Kenya; McCabe, Megan; and Lee, Ju Yun, "Amino Acid Quantification for DMC Biotechnologies" (2020). ENGS 89/90 Reports. 22.
https://digitalcommons.dartmouth.edu/engs89_90/22