Patterns of Human Herpesvirus-8 Oral Shedding among Diverse Cohorts of Human Herpesvirus-8 Seropositive Persons

Authors

Rachel A. Bender Ignacio, University of Washington - Seattle Campus
Jason D. Goldman, University of Washington - Seattle Campus
Amalia S. Magaret, University of Washington - Seattle Campus
Stacy Selke, University of Washington - Seattle Campus
Meei-Li Huang, University of Washington - Seattle Campus
Soren Gantt, University of British Columbia
Christine Johnston, University of Washington - Seattle Campus
Warren Phipps, University of Washington - Seattle Campus
Joshua Schiffer, University of Washington - Seattle Campus
Richard Zuckerman, Dartmouth College

Document Type

Article

Publication Date

2016

Publication Title

Infectious Agents and Cancer

Department

Geisel School of Medicine

Abstract

Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication (“shedding”) at mucosal sites, especially the oropharynx. Patterns of HHV-8 shedding are not well understood, and require elucidation to better predict risk of HHV-8 related malignancies in those infected. We sought to characterize patterns of HHV-8 oropharyngeal shedding among diverse cohorts that enrolled HHV-8 seropositive persons.

DOI

10.1186/s13027-016-0052-2

Dartmouth Digital Commons Citation

Bender Ignacio, Rachel A.; Goldman, Jason D.; Magaret, Amalia S.; Selke, Stacy; Huang, Meei-Li; Gantt, Soren; Johnston, Christine; Phipps, Warren; Schiffer, Joshua; and Zuckerman, Richard, "Patterns of Human Herpesvirus-8 Oral Shedding among Diverse Cohorts of Human Herpesvirus-8 Seropositive Persons" (2016). Dartmouth Scholarship. 1005.
https://digitalcommons.dartmouth.edu/facoa/1005