Document Type
Article
Publication Date
12-1-2021
Publication Title
Light: Science and Applications
Department
Thayer School of Engineering
Additional Department
Geisel School of Medicine
Abstract
Color vision is used throughout medicine to interpret the health and status of tissue. Ionizing radiation used in radiation therapy produces broadband white light inside tissue through the Cherenkov effect, and this light is attenuated by tissue features as it leaves the body. In this study, a novel time-gated three-channel camera was developed for the first time and was used to image color Cherenkov emission coming from patients during treatment. The spectral content was interpreted by comparison with imaging calibrated tissue phantoms. Color shades of Cherenkov emission in radiotherapy can be used to interpret tissue blood volume, oxygen saturation and major vessels within the body.
DOI
10.1038/s41377-021-00660-0
Original Citation
Alexander, D.A., Nomezine, A., Jarvis, L.A. et al. Color Cherenkov imaging of clinical radiation therapy. Light Sci Appl 10, 226 (2021). https://doi.org/10.1038/s41377-021-00660-0
Dartmouth Digital Commons Citation
Alexander, Daniel A.; Nomezine, Anthony; Jarvis, Lesley A.; Gladstone, David J.; Pogue, Brian W.; and Bruza, Petr, "Color Cherenkov imaging of clinical radiation therapy" (2021). Dartmouth Scholarship. 4118.
https://digitalcommons.dartmouth.edu/facoa/4118