Document Type

Article

Publication Date

12-1-2021

Publication Title

Light: Science and Applications

Department

Thayer School of Engineering

Additional Department

Geisel School of Medicine

Abstract

Color vision is used throughout medicine to interpret the health and status of tissue. Ionizing radiation used in radiation therapy produces broadband white light inside tissue through the Cherenkov effect, and this light is attenuated by tissue features as it leaves the body. In this study, a novel time-gated three-channel camera was developed for the first time and was used to image color Cherenkov emission coming from patients during treatment. The spectral content was interpreted by comparison with imaging calibrated tissue phantoms. Color shades of Cherenkov emission in radiotherapy can be used to interpret tissue blood volume, oxygen saturation and major vessels within the body.

DOI

10.1038/s41377-021-00660-0

Original Citation

Alexander, D.A., Nomezine, A., Jarvis, L.A. et al. Color Cherenkov imaging of clinical radiation therapy. Light Sci Appl 10, 226 (2021). https://doi.org/10.1038/s41377-021-00660-0

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