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Student Class

2028

Student Affiliation

WISP Intern

First Advisor

Dionna Kasper

First Advisor Department

Department of Biological Sciences

Description

This poster presents a summary of research progress from Dartmouth's Women in Science Project (WISP) internship investigating the impact of the microRNA miR-223 on lymphatic development using zebrafish as a model organism. The lymphatic system, a complex network of vessels and organs that transport fluid throughout the body, plays a crucial role in supporting bodily functions including immune response and tissue fluid homeostasis. However, many aspects of lymphatic development are not well understood. MicroRNAs, small noncoding segments of RNA that regulate the expression of mRNAs, are crucial for regulating development processes. Previously, expression of the microRNA miR-223 has been found in lymphatic endothelial cells, suggesting the importance of miR-223 in regulating the lymphatic development. This in-progress study investigates the impact of a mutation of the microRNA miR-223 (cd87) on the development of lymphatic system.

Publication Date

2025

Keywords

miR-223, lymphatic development, zebrafish, PCR

Investigating the Role of miR-223 in Zebrafish Lymphatic Development

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