This collection contains works by faculty from the Geisel School of Medicine.

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Submissions from 2015

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GEneSTATION 1.0: A Synthetic Resource of Diverse Evolutionary and Functional Genomic Data for Studying The Evolution of Pregnancy-Associated Tissues and Phenotypes, Mara Kim, Brian A. Cooper, Rohit Venkat, Julie B. Phillips, Haley R. Eidem, Jibril Hirbo, Sashank Nutakki, Scott M. Williams, Louis J. Muglia, J. Anthony Capra, Kenneth Petren, Patrick Abbot, Antonis Rokas, and Kriston L. McGary

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Macroscopic Optical Imaging Technique for Wide-Field Estimation of Fluorescence Depth in Optically Turbid Media for Application in Brain Tumor Surgical Guidance, Kolbein K. Kolste, Stephen C. Kanick, Pablo A. Valdés, Michael Jermyn, Brian C. Wilson, David W. Roberts, Keith D. Paulsen, and Frederic Leblond

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A Highly Stable Prefusion Rsv F Vaccine Derived from Structural Analysis of the Fusion Mechanism, Anders Krarup, Daphné Truan, Polina Furmanova-Hollenstein, Lies Bogaert, Pascale Bouchier, Ilona Bisschop, Myra Widjojoatmodjo, Roland Zahn, Hanneke Schuitemaker, Jason McLellan, and Johannes Langedijk

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Cyclic Di-GMP-Mediated Repression of Swarming Motility by Pseudomonas aeruginosa PA14 Requires the MotAB Stator, S. L. Kuchma, N. J. Delalez, L. M. Filkins, E. A. Snavely, J. P. Armitage, and G. A. O'Toole

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The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps, Mark J. Lee, Hong Liu, Bridget M. Barker, Brendan D. Snarr, Fabrice M. Gravelat, Qusai Al Abdallah, Christina Gavino, Shane R. Baistrocchi, Hanna Ostapska, Tianli Xiao, Benjamin Ralph, Norma V. Solis, Melanie Lehoux, Stefanie D. Baptista, and Arsa Thammahong

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Parasite Manipulation of the Invariant Chain and the Peptide Editor H2-DM Affects Major Histocompatibility Complex Class II Antigen Presentation during Toxoplasma gondii Infection, Louis-Philippe Leroux, Manami Nishi, Sandy El-Hage, Barbara A. Fox, David i Bzik, and Florence Dzierszinsk

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A Coding Variant in TMC8 (EVER2) Is Associated with High Risk HPV Infection and Head and Neck Cancer Risk, Caihua Liang, Karl T. Kelsey, Michael D. McClean, Brock C. Christensen, and Carmen J. Marsit

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Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus, Patrícia de Sousa Lima, Dawoon Chung, Alexandre Melo Bailão, Robert A. Cramer, and Célia Maria de Almeida Soares

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Fungal Mediator Tail Subunits Contain Classical Transcriptional Activation Domains, Zhongle Liu and Lawrence C. Myers

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RNA-Seq Analysis of Differential Splice Junction Usage and Intron Retentions by DEXSeq, Yafang Li, Xiayu Rao, William W. Mattox, Christopher I. Amos, and Bin Liu

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Yeast Integral Membrane Proteins Apq12, Brl1, and Brr6 Form a Complex Important for Regulation of Membrane Homeostasis and Nuclear Pore Complex Biogenesis, Museer A. Lone, Aaron E. Atkinson, Christine A. Hodge, Stéphanie Cottier, Fernando Martínez-Montañés, Shelley Maithel, Laurent Mène-Saffrané, Cole Cole, and Roger Schneiter

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Identification of a Family of Fatty Acid-Speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties, Jun Long, Robert Tokhunts, William M. Old, Stephane Houel, Jezabel Rodgriguez-Blanco, Samer Singh, Neal Schilling, Anthony J. Capobianco, Natalie G. Ahn, and David J. Robbins

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Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen, Jodie Lopez, Amina Bittame, Céline Massera, Virginie Vasseur, Gregory Effantin, Anne Valat, Celia Buaillon, Sophie Allart, Barbara A. Fox, Leah M. Rommereim, and David J. Bzik

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A Hierarchical Cascade of Second Messengers Regulates Pseudomonas aeruginosa Surface Behaviors, Yun Luo, Kun Zhao, Amy E. Baker, Sherry L. Kuchma, Kimberly A. Coggan, Matthew C. Wolfgang, Gerard C.L. Wong, and George A. O’Toole

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Placental DNA Methylation Related to Both Infant Toenail Mercury and Adverse Neurobehavioral Outcomes, Jennifer Zeynab Joukhadar Maccani, Devin C. Koestler, Barry Lester, E Andres Houseman, David A. Armstrong, Karl T. Kelsey, and Carmen J. Marsit

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Systems Level Analysis of Systemic Sclerosis Shows a Network of Immune and Profibrotic Pathways Connected with Genetic Polymorphisms, J. Matthew Mahoney, Jaclyn Taroni, Viktor Martyanov, Tammara A. A. Wood, Casey S. Greene, Patricia A. Pioli, Monique E. Hinchcliff, and Michael L. Whitfield

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A Mitochondria-Anchored Isoform of the Actin-Nucleating Spire Protein Regulates Mitochondrial Division, Uri Manor, Sadie Bartholomew, Gonen Golani, Eric Christenson, Michael Kozlov, Henry Higgs, James Spudich, and Jennifer Lippincott-Schwartz

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Influence of Environmental Exposure on Human Epigenetic Regulation, C. J. Marsit

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SPARCoC: A New Framework for Molecular Pattern Discovery and Cancer Gene Identification, Shiqian Ma, Daniel Johnson, Cody Ashby, Donghai Xiong, Carole L. Cramer, Jason H. Moore, Shuzhong Zhang, and Xiuzhen Huang

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Molecular Dyes used for Surgical Specimen Margin Orientation allow for Intraoperative Optical Assessment During Breast Conserving Surgery, David M. McClatchy, Venkataramanan Krishnaswamy, Stephen C. Kanick, Jonathan T. Elliott, Wendy A. Wells, Richard J. Barth Jr., Keith D. Paulsen, and Brian W. Pogue

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A Self-Lysis Pathway that Enhances the Virulence of a Pathogenic Bacterium, Kirsty A. McFarland, Emily L. Dolben, Michele LeRoux, Tracy K. Kambara, Kathryn Ramsey, Robin Kirkpatrick, Joseph Mougous, Deborah Hogan, and Simon Dove

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Shugoshin-1 Balances Aurora B Kinase Activity via PP2A to Promote Chromosome Bi-orientation, Amanda Meppelink, Lilian Kabeche, Martijn J.M. Vromans, Duane A. Compton, and Susanne M.A. Lens

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Willingness to test for BRCA1/2 in High Risk Women: Influenced by Risk Perception and Family Experience, rather than by Objective or Subjective Numeracy?, Talya Miron-Shatz, Yaniv Hanoch, Benjamin A. Katz, Glen M. Doniger, and Elissa M. Ozanne

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Amikacin Concentrations Predictive of Ototoxicity in Multidrug-Resistant Tuberculosis Patients, Chawangwa Modongo, Jotam G. Pasipanodya, Nicola M. Zetola, and Scott M. Williams

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Iron-Dependent Gene Expression in Actinomyces Oris, Matthew P. Mulé, David Giacalone, Kayla Lawlor, Alexa Golden, Caroline Cook, Thomas Lott, Elizabeth Aksten, George A. O'Toole, and Lori J. Bergeron

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Tumor Cell Targeting by Iron Oxide Nanoparticles is Dominated by Different Factors In Vitro versus In Vivo, Christian NDong, Jennifer A. Tate, Warren C. Kett, Jaya Batra, Eugene Demidenko, Lionel D. Lewis, P. Jack Hoopes, Tillmann U. Gerngross, and Karl E. Griswold

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Antibody-Mediated Targeting of Iron Oxide Nanoparticles to the Folate Receptor Alpha Increases Tumor Cell Association In Vitro and In Vivo, Christian Ndong, Seiko Toraya-Brown, Katsiaryna Kekalo, Ian Baker, Tillman U. Gerngross, Steven N. Fiering, and Karl E. Griswold

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A Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers, Geoffrey P. Noble, Daphne W. Wang, Daniel J. Walsh, Justin R. Barone, Michael B. Miller, Koren A. Nishina, Sheng Li, and Surachai Supattapone

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Monomethylarsonous Acid (MMAIII) Has an Adverse Effect on the Innate Immune Response of Human Bronchial Epithelial Cells to Pseudomonas Aeruginosa, Emily G. Notch, Britton C. Goodale, Roxanna Barnaby, Bonita Coutermarsh, Brent Berwin, Vivien F. Taylor, Brian P. Jackson, and Bruce A. Stanton

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Improving Health Outcomes through Concurrent HIV Program Scale-Up and Health System Development in Rwanda: 20 Years of Experience, Sabin Nsanzimana, Krishna Prabhu, Haley McDermott, Etienne Karita, Jamie I. Forrest, Peter Drobac, Paul Farmer, Edward J. Mills, and Agnes Binagwaho

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Yeast Vacuolar HOPS, Regulated by its Kinase, Exploits Affinities for Acidic Lipids and Rab:GTP for Membrane Binding and to Catalyze Tethering and Fusion, Amy Orr, William Wickner, Scott F. Rusin, Arminja N. Kettenbach, and Michael Zick

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Targeting Neddylation Induces DNA Damage and Checkpoint Activation and Sensitizes Chronic Lymphocytic Leukemia B Cells to Alkylating Agents, C Paiva, J C. Godbersen, A Berger, J R. Brown, and A V. Danilov

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Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1, Zachary M. Parker, Aisling A. Murphy, and David. A. Leib

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The preparatory Set: A Novel Approach to Understanding Stress, Trauma, and the Bodymind Therapies, Peter Payne and Mardi A. Crane-Godreau

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Somatic Experiencing: Using Interoception and Proprioception as Core Elements of Trauma Therapy, Peter Payne, Peter A. A. Levine, and Mardi A. Crane-Godreau

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IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Humans, Neil E. Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersom, Josep M. Anto, Bruce K. Armstrong, Andrea A. Baccarelli, Frederick A. Beland, Amy Berrington, Pier Alberto Bertazzi, Linda S. Birnbaum, Ross C. Brownson, John R. Bucher, Kenneth P. Cantor, Elisabeth Cardis, John W. Cherrie, David C. Christiani, Pierluigi Cocco, David Coggon, Pietro Comba, Paul A. Demers, John M. Dement, Jeroen Douwes, Ellen A. Eisen, Lawrence S. Engel, Richard A. Fenske, Lora E. Fleming, Tony Fletcher, Elizabeth Fontham, Francesco Forastiere, Rainer Frentzel-Beyme, Lin Fritschi, Michel Gerin, Marcel Goldberg, Philippe Grandjean, Tom K. Grimsrud, Per Gustavsson, Andy Haines, Patricia Hartge, Johnni Hansen, Michael Hauptmann, Dick Heederik, Kari Hemminki, Denis Hemon, Irva Hertz-Picciotto, Jane A. Hoppin, James Huff, Bengt Jarvholm, Daehee Kang, and Margaret R. Karagas

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Risk Factors for Hemorrhoids on Screening Colonoscopy, Anne F. Peery, Robert S. Sandler, Joseph A. Galanko, Robert S. Bresalier, Jane C. Figueiredo, Dennis J. Ahnen, Elizabeth L. L. Barry, and John A. Baron

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Sex-Specific Parental Effects on Offspring Lipid Levels, Irene M. Predazzi, Rafal S. Sobota, Serena Sanna, William S. Bush, Jacquelaine Bartlett, Jessica S. Lilley, Macrae F. Linton, David Schlessinger, Francesco Cucca, Sergio Fazio, and Scott M. Williams

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Tobramycin-Treated Pseudomonas aeruginosa PA14 Enhances Streptococcus constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System, Katherine E. E. Price, Amanda A. Naimie, Edward F. Griffin, Charles Bay, and George A. O'Toole

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Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas aeruginosa in a Cystic Fibrosis Model System of Biofilm Formation, Katherine E. Price, Giulia Orazi, Kathryn L. Ruoff, Wesley P. Hebert, George A. O'Toole, and Paul Mastoridis

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Fresolimumab Treatment Decreases Biomarkers and Improves Clinical Symptoms in Systemic Sclerosis Patients, Lisa M. Rice, Cristina M. Padilla, Sarah R. McLaughlin, Allison Mathes, Jessica Ziemek, Salma Goummih, Sashidhar Nakerakanti, Michael York, Giuseppina Farina, Michael L. Whitfield, Robert F. Spiera, Romy B. Christmann, Jessica K. Gordon, Janice Weinberg, and Robert Lafyatis

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Isolation of Mycobacterium Avium from Potable Water in Homes and Institutions of Patients with HIV Infection in Finland and the United States, Matti Ristola, Robert D. Arbeit, C. Fordham von Reyn, and C. Robert Horsburgh

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The Role of IL-27 in Susceptibility to Post-Influenza Staphylococcus Aureus Pneumonia, Keven M. Robinson, Benjamin Lee, Erich V Scheller, Sivanarayana Mandalapu, and Richard I. Enelow

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Enhancing Interferon Regulatory Factor 7 Mediated Antiviral Responses and Decreasing Nuclear Factor Kappa B Expression Limit HIV-1 Replication in Cervical Tissues, Christiane Rollenhage, Sherrill L. Macura, Melissa J. Lathrop, Todd A. Mackenzie, Gustavo F. Doncel, and Susana N. Asin

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Neuronal Interferon Signaling is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis, Pamela C. Rosato and David A. Leib

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META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies, Albert Rosenberger, Stefanie Friedrichs, Christopher I. Amos, Paul Brennan, Gordon Fehringer, Joachim Heinrich, Rayjean J. Hung, Thomas Muley, Martina Müller-Nurasyid, Angela Risch, and Heike Bickeböller

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Cohort of Birth Modifies the Association between FTO Genotype and BMI, James Niels Rosenquist, Steven F. Lehrer, A. James O'Malley, Alan M. Zaslavsky, Jordan W. Smoller, and Nicholas A. Christakis

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Leveraging Global Gene Expression Patterns to Predict Expression of Unmeasured Genes, James Rudd, René A. Zelaya, Eugene Demidenko, Ellen L. Goode, Casey S. Greene S. Greene, and Jennifer A. Doherty

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Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases, Shirley B. Russell, Joan C. Smith, Minjun Huang, Joel S. Trupin, and Scott M. Williams

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The Erv41–Erv46 Complex Serves as a Retrograde Receptor to Retrieve Escaped ER Proteins, Aya Shibuya, Neil Margulis, Romain Christiano, Tobias C. Walther, and Charles Barlowe

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Predicting Functional and Regulatory Divergence of a Drug Resistance Transporter Gene in the Human Malaria Parasite, Geoffrey H. Siwo, Asako Tan, Katrina A. Button-Simons, Upeka Samarakoon, Lisa A. Checkley, Richard S. Pinapati, and Michael T. Ferdig

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Pseudomonas Aeruginosa Reduces Vx-809 Stimulated F508del-Cftr Chloride Secretion by Airway Epithelial Cells, Bruce A. Stanton, Bonita Coutermarsh, Roxanna Barnaby, and Deborah Hogan

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A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus, Guillaume B. E. Stewart-Jones, Paul V. Thomas, Man Chen, Aliaksandr Druz, Gordon M. Joyce, Wing-Pui Kong, Mallika Sastry, Conque Soto, Yongping Yang, Baoshan Zhang, Lei Chen, Gwo-Yu Chuang, Ivelin S. Georgiev, and Jason S. McLellan

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Review of Biomedical Čerenkov Luminescence Imaging Applications, Kaveh Tanha, Ali Mahmoud Pashazadeh, and Brian W. Pogue

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Regulators Associated with Clinical Outcomes Revealed by Dna Methylation Data in Breast Cancer, Matthew H. Ung, Frederick S. Varn, Shaoke Lou, and Chao Cheng

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Systematic Analysis of Hematopoietic Gene Expression Profiles for Prognostic Prediction in Acute Myeloid Leukemia, Frederick S. Varn, Erik H. Andrews, and Chao Cheng

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Integrative Analysis of Survival-Associated Gene Sets in Breast Cancer, Frederick S. Varn, Matthew H. Ung, Shao Ke Lou, and Chao Cheng

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Alternative Use of DNA Binding Domains by the Neurospora White Collar Complex Dictates Circadian Regulation and Light Responses, Bin Wang, Xiaoying Zhou, Jennifer J. Loros, and Jay C. Dunlap

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Loregic: A Method to Characterize the Cooperative Logic of Regulatory Factors, Daifeng Wang, Koon-Kiu Yan, Cristina Sisu, Chao Cheng, Joel Rozowsky, William Meyerson, and Mark B. Gerstein

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Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes, Xinxin Wang, Leonard B. Hills, and Yina H. Huang

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The Role of Visualization and 3-D Printing in Biological Data Mining, Talia L. Weiss, Amanda Zieselman, Douglas P. Hill, Solomon G. Diamond, Li Shen, Andrew J. Saykin, and Jason H. Moore

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Dual use of VA and Non-VA Hospitals by Veterans with Multiple Hospitalizations, Alan N. West, Mary E. Charlton, and Mary Vaughan-Sarrazin

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Analysis of the Candida Albicans Phosphoproteome, S. D. Willger, Z. Liu, R. A. Olarte, M. E. Adamo, J E. Stajich, L C. Myers, A N. Kettenbach, and D A. Hogan

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Cell Type–Dependent Mechanisms for Formin-Mediated Assembly of Filopodia, Lorna E. Young, Ernest G. Heimsath, and Henry N. Higgs

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Optimization of Image Reconstruction for Magnetic Resonance Imaging–Guided Near-Infrared Diffuse Optical Spectroscopy in Breast, Yan Zhao, Michael A. Mastanduno, Shudong Jiang, Fadi EI-Ghussein, Jiang Gui, Brian W. Pogue, and Keith D. Paulsen

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Long Non Coding RNA MALAT1 Promotes Tumor Growth and Metastasis by Inducing Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma, Xuan Zhou, Su Liu, Guoshuai Cai, Lingping Kong, Tingting Zhang, Yu Ren, Yansheng Wu, Mei Mei, Lun Zhang, and Xudong Wang

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Targeting EZH2 Regulates Tumor Growth and Apoptosis Through Modulating Mitochondria Dependent Cell-Death Pathway in HNSCC, Xuan Zhou, Yu Ren, Lingping Kong, Guoshuai Cai, Shanshan Sun, Wangzhao Song, Yu Wang, Rui Jin, Lisha Qi, and Mei Mei

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Sec17 Can Trigger Fusion of Trans-SNARE Paired Membranes without Sec18, Michael Zick, Amy Orr, Matthew L. Schwartz, Alexey J. Merz, and William Wickner

Submissions from 2014

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Interventions to Improve Delivery of Isoniazid Preventive Therapy: an Overview of Systematic Reviews, Lisa V. Adams, Elizabeth A. Talbot, Karen Odato, Heather Blunt, and Karen R. Steingart

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Syndecan 4 is Required for Endothelial Alignment in Flow and Atheroprotective Signaling, Nicolas Baeyens, Mary Jo Mulligan-Kehoe, Federico Corti, David D. Simon, Tyler D. Ross, John M. Rhodes, and Thomas Z. Wang

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Epoxide-Mediated Differential Packaging of Cif and Other Virulence Factors into Outer Membrane Vesicles, A. E. Ballok, L. M. Filkins, J.. M. Bomberger, B. A. Stanton, and George A. O'Toole

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Calcium Supplementation Increases Blood Creatinine Concentration in a Randomized Controlled Trial, Elizabeth L. L. Barry, Leila A. A. Mott, Michal L. L. Melamed, Judith R. Rees, Anastasia Ivanova, Robert S. Sandler, Dennis J. Ahnen, Robert S. Bresalier, Robert W. Summers, Roberd M. Bostick, and John A. Baron

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The Impact of Waist Circumference on Function and Physical Activity in Older Adults: Longitudinal Observational Data from the Osteoarthritis Initiative, John A. Batsis, Alicia J. Zbehlik, Laura K. Barre, Todd A. Mackenzie, and Stephen J. Bartels

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GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways, Santanu Bhattacharya, Krishnendu Pal, Anil K. Sharma, Shamit K. Dutta, Julie S. Lau, Irene K. Yan, Enfeng Wang, Ahmed Elkhanany, Khalid M. Alkharfy, Arunik Sanyal, Tushar C. Patel, Suresh T. Chari, Mark R. Spaller, and Debabrata Mukhopadhyay

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Impact of Implementing Performance-Based Financing on Childhood Malnutrition in Rwanda, Agnes Binagwaho, Jeanine Condo, Claire Wagner, Fidele Ngabo, Corine Karema, Steve Kanters, Jamie I. Forrest, and Jean de Dieu Bizimana

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Serum and Glucocorticoid-Inducible Kinase1 Increases Plasma Membrane wt-CFTR in Human Airway Epithelial Cells by Inhibiting Its Endocytic Retrieval, Jennifer M. Bomberger, Bonita A. Coutermarsh, Roxanna L. Barnaby, J. Denry Sato, M. Christine Chapline, and Bruce A. Stanton

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Structural Features of the Pseudomonas fluorescens Biofilm Adhesin LapA Required for LapG-Dependent Cleavage, Biofilm Formation, and Cell Surface Localization, Chelsea D. Boyd, T. Jarrod Smith, Sofiane El-Kirat-Chatel, Peter D. Newell, Yves F. Dufrêne, and George A. O'Toole

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Health System Characteristics and Rates of Readmission After Acute Myocardial Infarction in the United States, Jeremiah R. Brown, Chiang-hua Chang, Weiping Zhou, Todd A. MacKenzie, David J. Malenka, and David C. Goodman

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Functional and Developmental Identification of a Molecular Subtype of Brain Serotonergic Neuron Specialized to Regulate Breathing Dynamics, Rachael D. Brust, Andrea E. Corcoran, George B. Richerson, Eugene Nattie, and Susan M. Dymecki

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Stoichiometries and Affinities of Interacting Proteins from Concentration Series of Solution Scattering Data: Decomposition by Least Squares and Quadratic Optimization, Himanshu Chandola, Tim E. Williamson, Bruce A. Craig, Alan M. Friedman, and Chris Bailey-Kellogg

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Candida albicans Ethanol Stimulates Pseudomonas aeruginosa WspR-Controlled Biofilm Formation as Part of a Cyclic Relationship Involving Phenazines, Annie I. Chen, Emily F. Dolben, Chinweike Okegbe, Colleen E. Harty, Yuriy Golub, Sandy Thao, Dae Gon Ha, Sven D. Willger, George A. O'Toole, Caroline S. Harwood, Lars E. P Dietrich, and Deborah A. Hogan

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Exome-Wide Association Study of Endometrial Cancer in a Multiethnic Population, Maxine M. Chen, Marta Crous-Bou, Veronica W. Setiawan, Jennifer Prescott, Sarah H. Olson, Nicolas Wentzensen, Amanda Black, Louise Brinton, Chu Chen, Constance Chen, Linda S. Cook, and Jennifer Doherty

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Modeling the Natural History and Detection of Lung Cancer Based on Smoking Behavior, Xing Chen, Millennia Foy, Marek Kimmel, and Olga Y. Gorlova

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Site-Specific Mutation of the Sensor Kinase GraS in Staphylococcus aureus Alters the Adaptive Response to Distinct Cationic Antimicrobial Peptides, Ambrose L. Cheung, Arnold S. Bayer, Michael R. Yeaman, Yan Q. Xiong, Alan J. Waring, Guido Memmi, and Niles Donegan

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Synthetic Triterpenoid Induces 15-PGDH Expression and Suppresses Inflammation-Driven Colon Carcinogenesis, Sung Hee Choi, Byung-Gyu Kim, Janet Robinson, Steve Fink, Min Yan, Michael B. Sporn, Sanford D. Markowitz, and John J. Letterio

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ChIP-Seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence, Dawoon Chung, Bridget M. Barker, Charles C. Carey, and Brittney Merriman

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Diverse Convergent Evidence in the Genetic Analysis of Complex Disease: Coordinating Omic, Informatic, and Experimental Evidence to Better Identify and Validate Risk Factors, Timothy H. Ciesielski, Sarah A. Pendergrass, Marquitta J. White, Nuri Kodaman, Rafal S. Sobota, Minjun Huang, Jacquelaine Bartlett, Jing Li, Qinxin Pan, Jiang Gui, Scott B. Selleck, Christopher I. Amos, Marylyn D. Ritchie, Jason H. Moore, and Scott M. Williams

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A Dietary-Wide Association Study (DWAS) of Environmental Metal Exposure in US Children and Adults, Matthew A. Davis, Diane Gilbert-Diamond, Margaret R. Karagas, Zhigang Li, Jason H. Moore, Scott M. Williams, and H. Robert Frost

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Megadalton-Node Assembly by Binding of Skb1 to the Membrane Anchor Slf1, Lin L. Deng, Ruth Kabeche, Ning Wang, Jian-Qiu Wu, and James B. Moseley

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Role of Adaptor TrfA and ClpPC in Controlling Levels of SsrA-Tagged Proteins and Antitoxins in Staphylococcus aureus, Niles P. Donegan, Jonathan S. Marvin, and Ambrose L. Cheung

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Tissue-Protective Effects of NKG2A in Immune-Mediated Clearance of Virus Infection, Kenneth H. Ely, Mitsuo Matsuoka, Matthew P. DeBerge, Jessica A. Ruby, Jun Liu, Mark J. Schneider, Yan Wang, Young S. Hahn, and Richard I. Enelow

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Safety with Ocrelizumab in Rheumatoid Arthritis: Results from the Ocrelizumab Phase III Program, Paul Emery, William Rigby, Paul P. Tak, Thomas Dörner, Ewa Olech, Carmen Martin, Laurie Millar, Helen Travers, and Elena Fisheleva

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Microwave Tomographic Imaging Utilizing Low-Profile, Rotating, Right Angle-Bent Monopole Antennas, N. R. Epstein, P. M. Meaney, and K. D. Paulsen

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Infection with Mers-Cov Causes Lethal Pneumonia in the Common Marmoset, Darryl Falzarano, Emmie de Wit, Friederike Feldmann, Angela L. Rasmussen, Atsushi Okumura, Xinxia Peng, Matthew J. Thomas, Neeltje van Doremalen, Elaine Haddock, Lee Nagy, Rachel LaCasse, Tingting Liu, Jiang Zhu, Jason S. McLellan, Dana P. Scott, Michael G. Katze, Heinz Feldmann, and Vincent J. Munster

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RNASEL and MIR146A SNP-SNP Interaction as a Susceptibility Factor for Non-Melanoma Skin Cancer, Shohreh F. Farzan, Margaret R. Karagas, Brock C. Christensen, Zhongze Li, Jacquelyn K. Kuriger, and Heather H. Nelson

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Genome-Wide Dna Methylation Profiles in Progression to In Situ and Invasive Carcinoma of the Breast with Impact on Gene Transcription and Prognosis, Thomas Fleischer, Arnoldo Frigessi, Kevin C. Johnson, Hege Edvardsen, Nizar Touleimat, Jovana Klajic, Margit LH Riis, Vilde D. Haakensen, Fredrik Wärnberg, Bjørn Naume, Åslaug Helland, Anne-Lise Børresen-Dale, Jörg Tost, Brock C. Christensen, and Vessela N. Kristensen

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Multiple Functional Risk Variants in a SMAD7 Enhancer Implicate a Colorectal Cancer Risk Haplotype, Barbara K. Fortini, Stephanie Tring, Sarah J. Plummer, Christopher K. Edlund, Victor Moreno, Robert S. Bresalier, Elizabeth L. Barry, Timothy R. Church, Jane C. Figueiredo, and Graham Casey

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Fatty Acids Increase Neuronal Hypertrophy of Pten Knockdown Neurons, Catherine J. Fricano, Tyrone DeSpenza, Paul W. Frazel, Meijie Li, A. James O'Malley, Gary Westbrook, and Bryan Luikart

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Methylation of Leukocyte DNA and Ovarian Cancer: Relationships with Disease Status and Outcome, Brooke L. Fridley, Sebastian M. Armasu, Mine S. Cicek, Melissa C. Larson, Chen Wang, Stacey J. Winham, Kimberly R. Kalli, and Devin C. Koestler

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Performance of the OraQuick HCV Rapid Antibody Test for Screening Exposed Patients in a Hepatitis C Outbreak Investigation, Fengxiang Gao, Elizabeth A. Talbot, Carol H. Loring, Jill J. Power, and Jodie Dionne-Odom