This collection contains works by faculty from the Geisel School of Medicine.

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Submissions from 2016

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Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries, Ai Tian, Hassina Benchabane, Zhenghan Wang, and Yashi Ahmed

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An FTO Gene Variant Moderates the Association between Parental Restriction and Child BMI, Alison Tovar, Jennifer A. Emond, Erin Hennessy, and Diane Gilbert-Diamond

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Bacterial corneal ulcer associated with common variable immune deficiency, Edmund Tsui, Jie Deng, Andrew N. Siedlecki, and Michael E. Zegans

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Methylation of the Leukocyte Glucocorticoid Receptor Gene Promoter in Adults: Associations with Early Adversity and Depressive, Anxiety and Substance-Use Disorders, A. R. Tyrka, S H. Parade, E S. Welch, K. K. Ridout, L Price, C Marsit, and L Carpenter

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Integrative analysis of cancer genes in a functional interactome, Matthew H. Ung, Chun-Chi Liu, and Chao Cheng

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Variation in Physician Practice Styles within and across Emergency Departments, Jessica Van Parys

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Integrative Analysis of Breast Cancer Reveals Prognostic Haematopoietic Activity and Patient-Specific Immune Response Profiles, Frederick S. Varn, Erik H. Andrews, David W. Mullins, and Chao Cheng

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Enhanced REC collaborative review through video-conferencing, Richard Waddell, Daima Bukini, Muhsin Aboud, Susan Adams, Eligius Lyamuy, Joyce Masalu, Elizabeth Bankert, and Lorri Wettemann

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Calcium-Mediated Actin Reset (Caar) Mediates Acute Cell Adaptations, Pauline Wales, Christian Schuberth, Roland Aufschnaiter, Johannes Fels, Ireth Garcia-Aguilar, Annette Janning, Christopher D. Dlugos, Marco Schaefer-Herte, Christoph Klingner, Mike Waelte, Julian Kuhlmann, Ekaterina Menis, Hockaday Kang Hockaday Kang, Kerstin C. Maier, Wenya Hou, Antonella Russo, and Henry N. Higgs

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Using Foreign Virtual Patients With Medical Students in Germany: Are Cultural Differences Evident and Do They Impede Learning?, Jens Walldorf, Tina Jähnert, Norman B. Berman, and Martin R. Fischer

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Application of RNAi-Induced Gene Expression Profiles for Prognostic Prediction in Breast Cancer, Yue Wang, Kenneth . M. K. Mark, Matthew H. Ung, Arminja Kettenbach, Todd Miller, Wei Xu, Wenqing Cheng Cheng, Tian Xia, and Chao Cheng

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Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling, Zhenghan Wang, Ofelia Tacchelly-Benites, Eungi Yang, and Yashi Ahmed

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The ADP-Ribose Polymerase Tankyrase Regulates Adult Intestinal Stem Cell Proliferation During Homeostasis in Drosophila, Zhenghan Wang, Ai Tian, Hassina Benchabane, Ofelia Tacchelly-Benites, Eungi Yang, Hisashi Nojima, and Yashi Ahmed

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The Fast-Evolving phy-2 Gene Modulates Sexual Development in Response to Light in the Model Fungus Neurospora crassa, Zheng Wang, Ning Li, Jigang Li, Jay C. Dunlap, Frances Trail, and Jeffrey P. Townsend

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Understanding and Meeting Information Needs for Patients with Posttraumatic Stress Disorder, Bradley V. Watts, Maha H. Zayed, Hilary Llewellyn-Thomas, and Paula P. Schnurr

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Comprehensive Cross-Population Analysis of High-Grade Serous Ovarian Cancer Supports No More Than Three Subtypes, Gregory P. Way, James Rudd, Chen Wang, and Habib Hamidi

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Without Explicit Targets, Does France Meet Minimum Volume Thresholds for Hip and Knee Replacement and Bariatric Surgeries?, William B. Weeks, Bruno Ventelou, and Zeynep Or

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A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons, Michael R. Williams, Catherine J. Fricano-Kugler, Stephanie A. Getz, Patrick D. Skelton, Jeonghoon Lee, Christian P. Rizzuto, Joseph S. Geller, Meijie Li, and Bryan W. Luikart

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Assessing Differences between Early and Later Adopters of Accountable Care Organizations Using Taxonomic Analysis, Frances M. Wu, Stephen M. Shortell, Valerie A. Lewis, Carrie H. Colla, and Elliott S. Fisher

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Genetic Susceptibility Loci of Idiopathic Interstitial Pneumonia do not Represent Risk for Systemic Sclerosis: a Case Control Study in Caucasian Patients, Minghua Wu, Shervin Assassi, Gloria A. Salazar, Claudia Pedroza, Olga Y. Gorlova, Wei V. Chen, Julio Charles, Miranda L. Taing, Kelley Liao, and Fredrick M. Wigley

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Segregation Analysis Suggests That a Genetic Reason May Contribute to "the Dress" Colour Perception, Feifei Xiao, Guoshuai Cai, and Heping Zhang

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Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues, Jinglin L. Xie, Nora Grahl, Trevor Sless, Michelle Leach, Sang Hu Kim, and Deborah Hogan

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iTAR: A Web Server for Identifying Target Genes of Transcription Factors using ChIP-Seq or ChIP-Chip Data, Chia-Chun Yang, Erik H. Andrews, Min-Hsuan Chen, and Wan-Yu Wang

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Wnt Pathway Activation by ADP-Ribosylation, Eungi Yang, Ofelia Tacchelly-Benites, Zhenghan Wang, Michael P. Randall, Ai Tian, Hassina Benchabane, Sarah Freemantle, Claudio Pikielny, Nicholas S. Tolwinski, Ethan Lee, and Yashi Ahmed

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A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer, Hua Yuan, Hongliang Liu, Zhensheng Liu, and Kouros Owzar

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Portable, Parallel 9-Wavelength Near-Infrared Spectral Tomography (NIRST) System for Efficient Characterization of Breast Cancer within the Clinical Oncology Infusion Suite, Yan Zhao, Brian W. Pogue, Steffen J. Haider, Jiang Gui, Roberta diFlorio-Alexander, Keith Paulsen, and Shudong Jiang

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CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins, Ashley A. Zurawel, Ruth Kabeche, Sonja E. DiGregorio, Lin Deng, Kartikeya M. Menon, Hannah Opaiko, James B. Moseley, and Surachai Supattapone

Submissions from 2015

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Proteolysis of Virulence Regulator Toxr is Associated with Entry of Vibrio Cholerae Into a Dormant State, Salvador Almagro-Moreno, Tae K. Kim, Karen Skorupski, and Ronald K. Taylor

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Intestinal Colonization Dynamics of Vibrio cholerae, Salvador Almagro-Moreno, Kali Pruss, and Ronald K. Taylor

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MicroRNA Molecular Profiling from Matched Tumor and Bio-Fluids in Bladder Cancer, David A. Armstrong, Benjamin B. Green, John D. Seigne, Alan R. Schned, and Carmen Marsit

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Numerical Chromosomal Instability Mediates Susceptibility to Radiation Treatment, Samuel F. Bakhoum, Lilian Kabeche, Matthew D. Wood, and Christopher D. Laucius

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Scoliosis Related Information on the Internet in China: Can Patients Benefit from This Information?, Hongda Bao, Feng Zhu, Fei Wang, Zhen Liu, Mike H. Bao, Shouyu He, Zezhang Zhu, and Yong Qiu

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The Trial of Calcium and Vitamin D for the Prevention of Colorectal Adenomas, John A. Baron, Elizabeth L. Barry, Leila A. Mott, and Judy R. Rees

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Axonal Activity In Vivo: Technical Considerations and Implications for the Exploration of Neural Circuits in Freely Moving Animals, Jeremy M. Barry

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Dynapenic Obesity and the Effect on Long-Term Physical Function and Quality of Life: Data from the Osteoarthritis Initiative, John A. Batsis, Alicia J. Zbehlik, Dawna Pidgeon, and Stephen J. Bartels

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The Gas Cylinder, the Motorcycle and the Village Health Team Member: A Proof-of-Concept Study for the Use of the Microsystems Quality Improvement Approach to Strengthen the Routine Immunization System in Uganda, Dorothy A. Bazos, Lea R. Ayers LaFave, Gautham Suresh, Kevin C. Shannon, Fred Nuwaha, and Mark E. Splaine

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Surgical Clipping versus Endovascular Intervention for the Treatment of Subarachnoid Hemorrhage Patients in New York State, Kimon Bekelis, Symeon Missios, Shannon Coy, Redi Rahmani, Robert J. Singer, and Todd A. MacKenzie

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New York State: Comparison of Treatment Outcomes for Unruptured Cerebral Aneurysms Using an Instrumental Variable Analysis, Kimon Bekelis, Symeon Missios, Shannon Coy, Robert J. Singer, and Todd A. Mackenzie

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Epigenome-Wide and Transcriptome-Wide Analyses Reveal Gestational Diabetes is Associated with Alterations in the Human Leukocyte Antigen Complex, Alexandra M. Binder, Jessica LaRocca, Corina Lesseur, Carmen J. Marsit, and Karin B. Michels

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Current Practice of Neonatal Resuscitation Documentation in North America: A Multi-Center Retrospective Chart Review, Matthew S. Braga, Prakash Kabbur, Pradeep Alur, and Michael H. Goodstein

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Site-Specific Immunomodulator: A Novel Treatment for Crohn's Disease, Brian Bressler, Kevin P. Bethel, Ralf Kleef, Sophie L. Reynolds, Simon Sutcliffe, David W. Mullins, and Hal Gunn

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Acute Kidney Injury Risk Prediction in Patients Undergoing Coronary Angiography in a National Veterans Health Administration Cohort with External Validation, Jeremiah R. Brown, Todd A. MacKenzie, Thomas M. Maddox, James Fly, Thomas T. Tsai, Mary E. Plomondon, Christopher D. Nielson, Edward D. Siew, Frederic S. Resnic, Clifton R. Baker, John S. Rumsfeld, and Michael E. Matheny

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IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge, Alayna K. Caffrey, Margaret M. Lehmann, Julianne M. Zickovich, Vanessa Espinosa, Kelly M. Shepardson, Christopher P. Watschke, Kimberly M. Hilmer, Arsa Thammahong, Bridget M. Barker, Amariliz Rivera, Robert A. Cramer, and Joshua J. Obar

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Maximizing the Impact of Training Initiatives for Health Professionals in Low-Income Countries: Frameworks, Challenges, and Best Practices, Corrado Cancedda, Paul E. Farmer, Vanessa Kerry, Tej Nuthulaganti, Kirstin W. Scott, Eric Goosby, and Agnes Binagwaho

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Whole Genome Capture of Vector-Borne Pathogens from Mixed DNA Samples: a Case Study of Borrelia burgdorferi, Giovanna Carpi, Katharine S. Walter, Stephen J. Bent, Anne Gatewood Hoen, Maria Diuk-Wasser, and Adalgisa Caccone

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Gene Expression Changes Reflect Clinical Response in a Placebo-Controlled Randomized Trial of Abatacept in Patients with Diffuse Cutaneous Systemic Sclerosis, Eliza F. Chakravarty, Viktor Martyanov, David Fiorentino, Tammara A. Wood, David J. Haddon, Justin A. Jarrell, Paul Utz, Mark Genovese, Michael Whitfield, and Lorinda Chung

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Workplace Safety Concerns among Co-workers of Responder Returning from Ebola-Affected Country, Benjamin P. Chan, Elizabeth R. Daly, and Elizabeth A. Talbot

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An Approach for Determining and Measuring Network Hierarchy Applied to Comparing the Phosphorylome and the Regulome, Chao Cheng, Erik Andrews, Koon-Kiu Yan, Matthew Ung, Daifeng Wang, and Mark Gerstein

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Mice Null for the Deubiquitinase USP18 Spontaneously Develop Leiomyosarcomas, Fadzai Chinyengetere, David J. Sekula, Yun Lu, Andrew J. Giustini, Aarti Sanglikar, Masanori Kawakami, and Tian Ma

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Maternal Psychiatric Disease and Epigenetic Evidence Suggest a Common Biology for Poor Fetal Growth, Timothy H. Ciesielski, Carmen J. Marsit, and Scott M. Williams

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Prenatal Predictors of Infant Self-Regulation: The Contributions of Placental DNA Methylation of NR3C1 and Neuroendocrine Activity, Elisabeth Conradt, Mary Fei, Linda LaGasse, Edward Tronick, Dylan Guerin, Daniel Gorman, Carmen J. Marsit, and Barry M. Lester

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International Genome-Wide Meta-Analysis Identifies New Primary Biliary Cirrhosis Risk Loci and Targetable Pathogenic Pathways, Heather J. Cordell, Younghun Han, George F. Mells, Yafang Li, Gideon M. Hirschfield, Casey S. Greene, Gang Xie, Brian D. Juran, Dakai Zhu, David C. Qian, James A.B Floyd, Katherine I. Morley, Daniele Prati, Ana Lleo, Daniele Cusi, Canadian–US PBC Consortium, Italian PBC Genetics Study Group, UK-PBC Consortium, M. Eric Gershwin, Carl A. Anderson, Konstantinos N. Lazaridis, Pietro Invernizzi, Michael F. Seldin, Richard N. Sandford, Christopher I. Amos, and Katherine A. Siminovitch

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Synthesis of Bioinspired Carbohydrate Amphiphiles that Promote and Inhibit Biofilms, Eric L. Dane, Alicia E. Ballok, George A. O'Toole, and Mark W. Grinstaff

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Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity, Arko Dasgupta, Chen-Hui Chen, ChangHwan Lee, Amy S. Gladfelter, Jay C. Dunlap, and Jennifer J. Loros

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Preliminary Analysis of in Utero Low-Level Arsenic Exposure and Fetal Growth Using Biometric Measurements Extracted from Fetal Ultrasound Reports, Matthew A. Davis, John Higgins, Zhigang Li, Diane Gilbert-Diamond, Emily R. Baker, Amar Das, and Margaret R. Karagas

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Exposure to Kynurenic Acid during Adolescence Increases Sign-Tracking and Impairs Long-Term Potentiation in Adulthood, Nicole E. DeAngeli, Travis P. Todd, Stephen E. Chang, Hermes H. Yeh, Pamela W. Yeh, and David J. Bucci

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Microarray Enriched Gene Rank, Eugene Demidenko

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Identifying Gene-Gene Interactions that are Highly Associated with Body Mass Index Using Quantitative Multifactor Dimensionality Reduction (QMDR), Rishika De, Shefali S. Verma, Fotios Drenos, and Emily R. Holzinger

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Tooth Retrospective Dosimetry Using Electron Paramagnetic Resonance: Influence of Irradiated Dental Composites, Céline M. Desmet, Andrej Djurkin, Ana Maria Dos Santos-Goncalvez, Ruhong Dong, Maciej M. Kmiec, Kyo Kobayashi, Kevin Rychert, Sébastien Beun, Julian G. Leprince, Gaëtane Leloup, Philippe Levêque, and Bernard Gallez

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Nucleus Accumbens Deep Brain Stimulation in a Rat Model of Binge Eating, W. T. Doucette, J. Y. Khokhar, and A. I. Green

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Logarithmic Intensity Compression in Fluorescence Guided Surgery Applications, Alisha V. DSouza, Huiyun Lin, Jason Gunn, and Brian W. Pogue

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Haemophilus Influenzae Responds to Glucocorticoids Used in Asthma Therapy by Modulation of Biofilm Formation and Antibiotic Resistance, Chris S. Earl, Tee Wooi Keong, Shi-qi An, Sarah Murdoch, Yvonne McCarthy, Junkal Garmendia, Joseph Ward, J Maxwell Dow, Liang Yang, George A. O'Toole, and Robert P. Ryan

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Review of Fluorescence Guided Surgery Visualization and Overlay Techniques, Jonathan T. Elliott, Alisha V. Dsouza, Scott C. Davis, Jonathan D. Olson, Keith Paulsen, David Roberts, and Brian Pogue

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Period-1 Encodes an ATP-Dependent RNA Helicase that Influences Nutritional Compensation of the Neurospora Circadian Clock, Jillian M. Emerson, Bradley M. Bartholomai, Carol S. Ringelberg, Scott E. Baker, Jennifer Loros, and Jay Dunlap

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Risk of Death from Cardiovascular Disease Associated with Low-level Arsenic Exposure Among Long-term Smokers in a US Population-based Study, Shohreh F. Farzan, Yu Chen, Judy R. Rees, M. Scot Zens, and Margaret Karagas

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Registered Report: Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis, Steven Fiering, Lay-Hong Ang, Judith Lacoste, Tim D. Smith, and Erin Griner

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Coculture of Staphylococcus aureus with Pseudomonas aeruginosa Drives S. aureus towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model, Laura M. Filkins, Jyoti A. Graber, Daniel G. Olson, Emily L. Dolben, Lee Lynd, Sabin Bhuju, and George A. O'Toole

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Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat, Laura M. Filkins and George A. O’Toole

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Nonreplicating, Cyst-Defective Type II Toxoplasma Gondii Vaccine Strains Stimulate Protective Immunity against Acute and Chronic Infection, Barbara Andrea Fox and David J. Bzik

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Three-Dimensional Matrix Fiber Alignment Modulates Cell Migration and MT1-MMP Utility by Spatially and Temporally Directing Protrusions, Stephanie I. Fraley, Pei-hsun Wu, Lijuan He, Yunfeng Feng, Ranjini Krisnamurthy, Gregory D. Longmore, and Denis Wirtz

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Spectral Gene Set Enrichment (SGSE), H Robert Frost, Zhigang Li, and Jason H. Moore

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Principal Component Gene Set Enrichment (Pcgse), H. Robert Frost, Zhigang Li, and Jason H. Moore

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Development of the CRISPR/Cas9 System for Targeted Gene Disruption in Aspergillus Fumigatus, Kevin Fuller, Shan Chen, Jennifer J. Loros, and Jay C. Dunlap

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Electrocardiographic Patch Devices and Contemporary Wireless Cardiac Monitoring, Erik Fung, Marjo-Riitta Järvelin, Rahul N. Doshi, Jerold S. Shinbane, Steven K. Carlson, Luanda P. Grazette, Philip M. Chang, Rajbir S. Sangha, Heikki V. Huikuri, and Nicholas S. Peters

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Serum Iron Level is Associated with Time to Antibiotics in Cystic Fibrosis, Alex H. Gifford, Dana B. Dorman, Lisa A. Moulton, Jennifer E. Helm, Mary M. Griffin, and Todd A. Mackenzie

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Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein, Morgan S.A Gilman, Syed M. Moin, Vicente Mas, Man Chen, Nita K. Patel, Kari Kramer, Qing Zhu, Stephanie C. Kabeche, Azad Kumar, Concepción Palomo, Tim Beaumont, Ulrich Baxa, Nancy D. Ulbrandt, José A. Melero, Barney S. Graham, and Jason S. McLellan

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A Forward Genetic Screen Reveals Novel Independent Regulators of Ulbp1, an Activating Ligand for Natural Killer Cells, Benjamin G Gowen, Bryan Chim, Caleb D. Marceau, Trever T Greene, Patrick Burr, Jeanmarie R. Gonzalez, Charles Hesser, Peter A. Dietzen, Teal Russell, Alexandre Iannello, Laurent Coscoy, and Charles L. Sentman

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Early Inflammatory Mediator Gene Expression in Two Models of Traumatic Brain Injury: Ex Vivo Cortical Slice in Mice and In Vivo Cortical Impact in Piglets, David J. Graber, Beth A. Costine, and William F. Hickey

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Mitochondrial Activity and Cyr1 are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways, Nora Grahl, Elora G. Demers, Allia K. Lindsay, Colleen E. Harty, Sven D. Wilger, Amy E. Piispanen, and Deborah A. Hogan

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Selective Involvement of the Checkpoint Regulator VISTA in Suppression of B-Cell, but Not T-Cell, Responsiveness by Monocytic Myeloid-Derived Suppressor Cells from Mice Infected with an Immunodeficiency-Causing Retrovirus, Kathy A. Green, Li Wang, Randolph J. Noelle, and William R. Green

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Testing Multiple Hypotheses through IMP weighted FDR Based on a Genetic Functional Network with Application to a New Zebrafish Transcriptome Study, Jiang Gui, Casey S. Greene, Con Sullivan, Walter Taylor, Jason H. Moore, and Carol Kim

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MCL1 Enhances the Survival of CD8+ Memory T Cells after Viral Infection, Jingang Gui, Zhuting Hu, Ching-Yi Tsai, Tian Ma, Yan Song, Amanda Morales, Li-Hao Huang, Ethan Dmitrovsky, Ruth Craig, and Edward Usherwood

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Prediction of the Gene Expression in Normal Lung Tissue by the Gene Expression in Blood, Justin W. Halloran, Dakai Zhu, David C. Qian, Jinyoung Byun, Olga Y. Gorlova, Christopher I. I. Amos, and Ivan P. Gorlov

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Links between Anr and Quorum Sensing in Pseudomonas aeruginosa Biofilms, John H. Hammond, Emily F. Dolben, T. Jarrod Smith, Sabin Bhuju, and Deborah Hogan

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Addressing Therapeutic Options for Ebola Virus Infection in Current and Future Outbreaks, Azizul Haque, Didier Hober, and Joel Blondiaux

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Obesity Early in Adulthood Increases Risk but Does Not Affect Outcomes of Hepatocellular Carcinoma, Manal M. Hassan, Reham Abdel-Wahab, Ahmed Kaseb, Ahmed Shalaby, Alexandria Phan, Hashem El-Serag, Ernest Hawk, Jeff Morris, Kanwal Pratap Singh Raghav, Ju-Seog Lee, Jean-Nicolas Vauthey, Gehan Bortus, Harrys Torres, Christopher Amos, Robert Wolff, and Donghui Li

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Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of Pseudomonas aeruginosa Mediated by Increased Expression of Phage-Related Genes, Gary E. E. Heussler, Kyle C. Cady, Katja Koeppen, Sabin Bhuju, Bruce A. Stanton, and George A. O’Toole

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Functional Dyadicity and Heterophilicity of Gene-Gene Interactions in Statistical Epistasis Networks, Ting Hu, Angeline S. Andrew, Margaret R. Karagas, and Jason H. Moore

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Trends in Initial Management of Prostate Cancer in New Hampshire, Johann Ingimarsson, Maria Celaya, Michael Laviolette, Judy R. Rees, and Elias Hyams

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Validating Estimates of Prevalence of Non-Communicable Diseases Based on Household Surveys: The Symptomatic Diagnosis Study, Spencer L. James, Minerva Romero, Dolores Ramírez-Villalobos, and Sara Gómez

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Association between Arsenic Exposure from Drinking Water and Longitudinal Change in Blood Pressure among HEALS Cohort Participants, Jieying Jiang, Mengling Liu, Faruque Parvez, Binhuan Wang, Fen Wu, Mahbub Eunus, Sripal Bangalore, Jonathan D. Newman, Alauddin Ahmed, Tariqul Islam, Muhammed Rakibuz-Zaman, Rabiul Hasan, Golam Sarwar, Diane Levy, Vesna Slavkovich, Maria Argos, Molly Scannell Bryan, Shohreh F. Farzan, Richard B. Hayes, Joseph H. Graziano, Habibul Ahsan, and Yu Chen

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Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and Immunopathology, Yike Jiang, Xiaotang Yin, Patrick M. Stuart, and David A. Leib

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The Happy Older Latinos are Active (HOLA) Health Promotion and Prevention Study: Study Protocol for a Pilot Randomized Controlled Trial, Daniel E. Jimenez, Charles F. Reynolds, Margarita Alegría, Philip Harvey, and Stephen Bartels

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Actin Filaments Target the Oligomeric Maturation of the Dynamin Gtpase Drp1 to Mitochondrial Fission Sites, Wei-ke Ji, Anna L. Hatch, Ronald A. Merrill, Stefan Strack, and Henry N. Higgs

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DNA Methylation in Ductal Carcinoma in Situ Related with Future Development of Invasive Breast Cancer, Kevin C. Johnson, Devin C. Koestler, Thomas Fleischer, Panpan Chen, Erik G. Jenson, Jonathan D. Marotti, Tracy Onega, Vessela N. Kristenen, and Brock C. Christensen

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Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts, Michael E. Johnson, J. Matthew Mahoney, Jaclyn Taroni, Jennifer L. Sargent, Eleni Marmarelis, Ming-ru Wu, John Varga, Monique E. Hinchcliff, and Michael L. Whitfield

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In Vivo Cigarette Smoke Exposure Decreases CCL20, SLPI, and BD-1 Secretion by Human Primary Nasal Epithelial Cells, James Jukosky, Benoit J. Gosselin, Leah Foley, Tenzin Dechen, Steven Fiering, and Mardi A. Crane-Godreau

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Eisosomes Provide Membrane Reservoirs for Rapid Expansion of the Yeast Plasma Membrane, Ruth Kabeche, Louisa Howard, and James B. Moseley

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Social Communication of Predator-Induced Changes in Drosophila Behavior and Germ Line Physiology, Balint Z. Kacsoh, Julianna Bozler, Mani Ramaswami, and Giovanni Bosco

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Total Pancreatectomy with Islet Autologous Transplantation: The Cure for Chronic Pancreatitis?, Samuel J. Kesseli, Kerrington A. Smith, and Timothy B. Gardner