This collection contains works by faculty from the Geisel School of Medicine.

Follow


Submissions from 1996

PDF

Cloning of Human Acetyl-CoA Carboxylase-Beta and its Unique Features., Joohun Ha, Jung-Kee Lee, Kyung-Sup Kim, Lee A. Witters, and Ki-Han Kim

PDF

GTPase-deficient G Alpha 16 and G Alpha q Induce PC12 Cell Differentiation and Persistent Activation of cJun NH2-terminal Kinases., Lynn E. Heasley, Brooke Storey, Gary R. Fanger, Laura Butterfield, J Zamarripa, D Blumberg, and R A. Maue

PDF

F(c)gammaRI-Targeted Fusion Proteins result in Efficient Presentation by Human Monocytes of Antigenic and Antagonist T Cell Epitopes, Chunlei Liu, Joel Goldstein, Robert F. Graziano, Jia He, Jeremiah K. O'Shea, Yashwant Deo, and Paul M. Guyre

PDF

Physical Linkage of the Vibrio Cholerae Mannose-Sensitive Hemagglutinin Secretory and Structural Subunit Gene Loci: Identification of the Mshg Coding Sequence., Jane W. Marsh, Daxi Sun, and Ronald K. Taylor

PDF

A Truncated Form of the Pho80 cyclin of Saccharomyces Cerevisiae Induces Expression of a Small Cytosolic Factor which Inhibits Vacuole Inheritance., Teresa Nicolson, Barbara Conradt, and William Wickner

PDF

NuMA Assembles Into an Extensive Filamentous Structure When Expressed in the Cell Cytoplasm, Alejandro Saredi, Louisa Howard, and Duane A. Compton

PDF

Toxin-coregulated Pilus, but Not Mannose-sensitive Hemagglutinin, is Required for Colonization by Vibrio Cholerae O1 El Tor Biotype and O139 Strains., K Helene Thelin and Ronald K. Taylor

PDF

Disruption of the Cbfa2 Gene Causes Necrosis and Hemorrhaging in the Central Nervous System and Blocks Definitive Hematopoiesis., Qing Wang, Terryl Stacy, Michael M Binder, Miguel Marin-Padilla, Arlene H. Sharpe, and Nancy A. Speck

Submissions from 1995

PDF

Strain-Dependent Variation in Carbon Source Regulation of Nucleus-Encoded Mitochondrial Proteins of Saccharomyces Cerevisiae., Timothy A. Brown and Bernard L. Trumpower

PDF

A TEF-1-independent Mechanism for Activation of the Simian Virus 40 (SV40) Late Promoter by Mutant SV40 Large T Antigens., Paul Casaz, Phillip W. Rice, Charles N. Cole, and Ulla Hansen

PDF

Role of 4-1BB Ligand in Costimulation of T Lymphocyte Growth and its Upregulation on M12 B Lymphomas by cAMP, M. A. DeBenedette, N. R. Chu, K. E. Pollok, J. Hurtado, William F. Wade, Byoung S. Kwon, and Tania H. Watts

PDF

Gas1-induced Growth Suppression Requires a Transactivation-independent p53 Function., Giannino Del Sal, Elisabetta M. Ruaro, Rene Utrera, and Charles N. Cole

PDF

Survival of Immunoglobulin G-opsonized Toxoplasma gondii in Nonadherent Human Monocytes., Camilo E. Fadul, Jacqueline Y. Channon, and Lloyd H. Kasper

PDF

The leukemic core binding factor beta-smooth muscle myosin heavy chain (CBF beta-SMMHC) chimeric protein requires both CBF beta and myosin heavy chain domains for transformation of NIH 3T3 cells., Amitav Hajra, Pu Liu, Qing Wang, and Christine Kelley

PDF

A Toxoplasma gondii-derived Factor(s) Stimulates Immune Downregulation: An in Vitro Model., Sakhina Haque, Azizul Haque, and Lloyd H. Kasper

PDF

Asbestos Induces Nuclear Factor Kappa B (NF-kappa B) DNA-Binding Activity and NF-Kappa B-Dependent Gene Expression in Tracheal Epithelial Cells., Yvonne M. Janssen, Aaron Barchowsky, Melinda Treadwell, Kevin E. Driscoll, and B T. Mossman

PDF

Mutation or Deletion of the Saccharomyces Cerevisiae RAT3/NUP133 Gene causes Temperature-Dependent Nuclear Accumulation of Poly(A)+ RNA and Constitutive Clustering of Nuclear Pore Complexes, Ou Li, Catherine V. Heath, David C. Amberg, Thomas C. Dockendorff, Connie S. Copeland, Michael Snyder, and Charles N. Cole

PDF

Survival of Mouse Pancreatic Islet Allografts in Recipients Treated with Allogeneic Small Lymphocytes and Antibody to CD40 Ligand., David C. Parker, Dale L. Greiner, Nancy E. Phillips, Michael C. Appel, Alan W. Steele, Fiona H. Durie, Randolph J. Noelle, John P. Mordes, and Aldo A. Rossini

PDF

A Novel Translational Regulation Function for the Simian Virus 40 Large-T Antigen Gene., Prithi Rajan, Sathyamagalam Swaminathan, Jiyue Zhu, and Charles N. Cole

PDF

The GTP-Bound Form of the Yeast Ran/TC4 Homologue Blocks Nuclear Protein Import and Appearance of Poly(A)+ RNA in the Cytoplasm., Gabriel Schlenstedt, Claudio Saavedra, Jonathan D. Loeb, Charles N. Cole, and Pamela A. Silver

PDF

Transactivation of the Moloney Murine Leukemia Virus and T-cell Receptor Beta-Chain Enhancers by cbf and ets Requires Intact Binding Sites for Both Proteins., Wanwen Sun, Barbara J. Graves, and Nancy A. Speck

PDF

Polyclonal Mycobacterium Avium Infections in Patients with AIDS: Variations in Antimicrobial Susceptibilities of Different Strains of M. Avium Isolated from the Same Patient., C Fordham von Reyn, Nicholas J. Jacobs, Robert D. Arbeit, Joe N. Maslow, and S Niemczyk

PDF

Patient Reactions to a Program Designed to Facilitate Patient Participation in Treatment Decision for Benign Prostatic Hyperplasia, John E. Wennberg

PDF

The Effect of a Shared Decisionmaking Program on Rates of Surgery for Benign Prostatic Hyperplasia. Pilot Results., John E. Wennberg

PDF

The Nascent-Polypeptide-Associated Complex: Having a "NAC" for Fidelity in Translocation., William Wickner

PDF

Protein-Peptide Interactions Analyzed with the Yeast Two-Hybrid System, Meijia Yang, Zining Wu, and Stanley Fields

PDF

Transcriptional Activity of Core Binding Factor-Alpha (AML1) and Beta Subunits on Murine Leukemia Virus Enhancer Cores., Ari L. Zaiman, Amy F. Lewis, Barbara E. Crute, N. A. Speck, and Jack Lenz

Submissions from 1994

PDF

Circadian Clock Locus Frequency: Protein Encoded by a Single Open Reading Frame Defines Period Length and Temperature Compensation., Benjamin D. Aronson, Keith A. Johnson, and Jay C. Dunlap

PDF

Antibody to the Ligand of CD40, Gp39, Blocks the Occurrence of the Acute and Chronic Forms of Graft-Vs-Host Disease, F H. Durie, A Aruffo, J Ledbetter, and K M. Crassi

PDF

CD40 Ligand Expression is Defective in a Subset of Patients with Common Variable Immunodeficiency., Mary Farrington, Laura S. Grosmaire, Shigeaki Nonoyama, Susanna H. Fischer, Diane Hollenbaugh, Jeffrey A. Ledbetter, and R. J. Noelle

PDF

Adoptive Transfer of Polyclonal and Cloned Cytolytic T Lymphocytes (CTL) Specific for Mouse AIDS-associated Tumors is Effective in Preserving CTL Responses: A Measure of Protection Against LP-BM5 Retrovirus-induced Immunodeficiency., William R. Green, Kathy A. Green, and Karen M. Crassi

PDF

Antiparasitic and Antiproliferative Effects of Indoleamine 2,3-dioxygenase Enzyme Expression in Human Fibroblasts., Sohan L. Gupta, Joseph M. Carlin, Padma Pyati, Wei Dai, Elmer R. Pfefferkorn, and Martin J. Murphy Jr

PDF

Impairment of the Cellular Immune Response in Acute Murine Toxoplasmosis: Regulation of Interleukin 2 Production and Macrophage-mediated Inhibitory Effects., Sakhina Haque, Imtiaz Khan, Azizul Haque, and Lloyd Kasper

PDF

The Random Inactivation of the X Chromosome Carrying the Defective Gene Responsible for X-Linked Hyper IgM Syndrome (X-HIM) in Female Carriers of HIGM1, D Hollenbaugh, L H. Wu, H D. Ochs, and S Nonoyama

PDF

Subunit Dynamics in Escherichia Coli Preprotein Translocase., John C. Joly, Marilyn R. Leonard, and William T. Wickner

PDF

Interleukin-12 Enhances Murine Survival Against Acute Toxoplasmosis., Imtiaz A. Khan, Tadashi Matsuura, and Lloyd H. Kasper

PDF

Binding of Matrix Attachment Regions to Lamin Polymers Involves Single-Stranded Regions and the Minor Groove., M. E. Eva Ludérus, Jan L. den Blaauwen, Oncko J. de Smit, Duane A. Compton, and Roel van Driel

PDF

Contrast Enhancement of Medical Images using Multiscale Edge Representation, Jian Lu, Dennis M. Healy Jr., and John B. Weaver

PDF

BCL-2 Protein Expression is Widespread in the Developing Nervous-System and Retained in the Adult PNS, Diane E. Merry, Deborah J. Veis, William F. Hickey, and Stanley J. Korsmeyer

PDF

The Amino-terminal Functions of the Simian Virus 40 Large T Antigen Are Required to Overcome Wild-type p53-Mediated Growth Arrest of Cells., Robin S. Quartin, Charles N. Cole, James M. Pipas, and Arnold J. Levine

PDF

Polyclonal Infections Due to Mycobacterium Avium Complex in Patients with AIDS Detected by Pulsed-field Gel Electrophoresis of Sequential Clinical Isolates., Alexander M. Slutsky, Robert D. Arbeit, Thomas W. Barber, Josiah Rich, and C Fordham von Reyn

PDF

A Thyroid Hormone-Regulated Gene in Xenopus Laevis Encodes a Type III Iodothyronine 5-Deiodinase., Donald L. St Germain, Robert Schwartzman, Walburga Croteau, Akira Kanamori, Zhou Wang, Donald D. Brown, and Valerie Galton

PDF

Comparison of Cytotoxic Properties of Neonatal and Adult Neutrophils and Monocytes and Enhancement by Cytokines., E . R. Stiehm, R. L. Roberts, B. J. Ank, S. Plaeger-Marshall, N. Salman, L. Shen, and M. W. Fanger

PDF

ROC Curve Regression Analysis: the Use of Ordinal Regression Models for Diagnostic Test Assessment, Anna N.A. Tosteson, Milton C. Weinstein, Jack Wittenberg, and Colin B. Begg

PDF

Regulation of Collagenase Gene Expression by IL-1 Beta Requires Transcriptional and Post-Transcriptional Mechanisms, Matthew P. Vincenti, Charles I. Coon, Oneil Lee, and Constance E. Brinckerhoff

PDF

Cooperative Binding of Ets-1 and Core Binding Factor to DNA., David Wotton, Jacques Ghysdael, Shuwen Wang, Nancy A. Speck, and Michael J. Owen

Submissions from 1993

PDF

The Interplay of Light and the Circadian Clock. Independent Dual Regulation of Clock-Controlled Gene Ccg-2(eas), Guiseppina Arpaia, Jennifer J. Loros, Jay C. Dunlap, Giorgio Morelli, and Guiseppe Macino

PDF

Isolation of Interleukin 2-Induced Immediate-Early Genes., Carol Beadling, Kirk W. Johnson, and Kendall A. Smith

PDF

Increased Collagen-Linked Pentosidine Levels and Advanced Glycosylation End Products in Early Diabetic Nephropathy, Paul J. Beisswenger, Lynn L. Moore, Truls Brinck-Johnsen, and Thomas J. Curphey

PDF

Selective Modulation of Human Natural Killer Cells in vivo after Prolonged Infusion of Low Dose Recombinant Interleukin 2, Michael A. Caligiuri, Christine Murray, Michael J. Robertson, Eunice Wang, Keith Cochran, Christine Cemeron, Peter Schow, Mary E. Ross, Thomas R. Klumpp, Robert J. Soiffer, Kendall A. Smith, and Jerome Ritz

PDF

Porphyrin Accumulation and Export by Isolated Barley (Hordeum vulgare) Plastids (Effect of Diphenyl Ether Herbicides), Judith M. Jacobs and Nicholas J. Jacobs

PDF

Lithium Phthalocyanine: A Probe for Electron Paramagnetic Resonance Oximetry in Viable Biological Systems., K. J. Liu, P. Gast, M. Moussavi, S. W. Norby, N Vahidi, and T Walczak

PDF

Two Factors that Bind to Highly Conserved Sequences in Mammalian Type C Retroviral Enhancers., Nancy R. Manley, Mary M. O'Connell, Wanwen Sun, Nancy A. Speck, and Nancy Hopkins

PDF

Sequence Specificity of the Core-Binding Factor, Irena N. Melnikova, Barbara E. Crute, Shuwen Wang, and Nancy A. Speck

PDF

Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines., Kenneth Peterson, Galynn Zitnik, Clare Huxley, and Christopher Lowrey

PDF

Efficient Transcriptional Activation of Many Simple Modular Promoters by Simian Virus 40 Large T Antigen., Philip W. Rice and Charles N. Cole

PDF

Characterization of a Protein that Binds Multiple Sequences in Mammalian Type C Retrovirus Enhancers., Wanwen Sun, Mary M. O'Connell, and Nancy A. Speck

PDF

Common Elements in Interleukin 4 and Insulin Signaling Pathways in Factor-Dependent Hematopoietic Cells., Ling-Mei Wang, Achsah D. A D Keegan, Weiqun Li, and Gustav E. Lienhard

PDF

Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor., Shuwen Wang, Qing Wang, Barbara E. Crute, Irena N. Melnikova, Susanna R. Keller, and Nancy A. Speck

PDF

Could Distance be a Proxy for Severity-of-Illness? A Comparison of Hospital Costs in Distant and Local Patients., H G. Welch, E B. Larson, and W P. Welch

PDF

Molecular Cloning of Infectious Ecotropic Murine Leukemia Virus AK7 from an emv-14-positive AKXL-5 Mouse and the Resistance of AK7 to Recognition by Cytotoxic T Lymphocytes., Hillary D. White, William R. Green, and Nuria R. Giné

Submissions from 1992

PDF

Mechanisms of Interference with Simian Virus 40 (SV40) DNA Replication by Trans-Dominant Mutants of SV40 Large T Antigen, Christine M. Bentivoglio, Jiyue Zhu, and Charles Cole

PDF

Cytolytic T Lymphocytes Specific for Tumors and Infected Cells from Mice with a Retrovirus-induced Immunodeficiency Syndrome., Jennifer G. Erbe, Kathy A. Green, Karen M. Crassi, Herbert C. Morse, and W R. Green

PDF

Differentiation of Renal Beta-Intercalated Cells to Alpha-Intercalated and Principal Cells in Culture., Geza Fejes-Tóth and Aniko Náray-Fejes-Tóth

PDF

On the Mechanism of Parathyroid Hormone Stimulation of Calcium Uptake by Mouse Distal Convoluted Tubule Cells, F A. Gesek and A. Friedman

PDF

Mechanism of Calcium Transport Stimulated by Chlorothiazide in Mouse Distal Convoluted Tubule Cells., Frank A. Gesek and Peter A. Friedman

PDF

Modulation of Cisplatin Sensitivity and Growth Rate of an Ovarian Carcinoma Cell Line by Bombesin and Tumor Necrosis Factor-Alpha., Seiji Isonishi, Antti P. Jekunen, Doreen K. Hom, Alan Eastman, Peter S. Edelstein, Franz B. Thiebaut, Randolph D. Christen, and Stephen B. Howell

PDF

Differential Regulation of Collagenase Gene Expression by Retinoic Acid Receptors--Alpha, Beta And Gamma, Luying Pan, Stephen H. Chamberlain, David T. Auble, and Constance E. Brinckerhoff

PDF

A Phorbol Ester Response Element within the Human T-Cell Receptor Beta-Chain Enhancer., Haydn M. Prosser, David Wotton, Anne Gegonne, Jacques Ghysdael, Shuwen Wang, Nancy A. Speck, and Michael J. Owen

PDF

Indistinguishable Nuclear Factor Binding to Functional Core Sites of the T-Cell Receptor Delta and Murine Leukemia Virus Enhancers., Juan M. Redondo, Jeffrey L. Pfohl, Cristina Hernandez-Munain, Shuwen Wang, Nancy A. Speck, and Michael S. Krangel

PDF

Adenosine Regulates a Chloride Channel via Protein Kinase C and a G Protein in a Rabbit Cortical Collecting Duct Cell Line., Erik M. Schwiebert, Katherine H. Karlson, Peter A. Friedman, Paul Dietl, William S. Spielman, and Bruce Stanton

PDF

Purification of Core-Binding Factor, a Protein that Binds the Conserved Core Site in Murine Leukemia Virus Enhancers., Shuwen W. Wang and Nancy A. Speck

PDF

Transformation of a Continuous Rat Embryo Fibroblast Cell Line Requires Three Separate Domains of Simian Virus 40 Large T Antigen., Jiyue Zhu, Philip W. Rice, Lisa Gorsch, Marina Abate, and Charles N. Cole

Submissions from 1991

PDF

Reaction of Chromium(VI) with Glutathione or with Hydrogen Peroxide: Identification of Reactive Intermediates and their Role in Chromium(VI)-Induced DNA Damage, J Aiyar, H Berkovits, R Floyd, and K Wetterhahn

PDF

Association of Circulating Receptor Fc Gamma RIII-Positive Monocytes in AIDS Patients with Elevated Levels of Transforming Growth Factor-Beta, J B. Allen, H L. Wong, P M. Guyre, and G L. Simon

PDF

Fc Receptors for IgG (Fc gamma Rs) on Human Monocytes and Macrophages Are Not Infectivity Receptors for Human Immunodeficiency Virus Type 1 (HIV-1): Studies Using Bispecific Antibodies to Target HIV-1 to Various Myeloid Cell Surface Molecules, including the Fc Gamma R., R I. Connor, N B. Dinces, A L. Howell, J L. Romet-Lemonne, J L. Pasquali, and M W. Fanger

PDF

Evidence for Attenuation of Myo-Inositol Uptake, Phosphoinositide Turnover and Inositol Phosphate Production in Aortic Vasculature of Rats During Pregnancy, Kirk P. Conrad, Susan A. Barrera, Peter A. Friedman, and Vicki M. Schmidt

PDF

A Polymerase Chain Reaction-Based Method to Detect Cisplatin Adducts in Specific Genes, M M. Jennerwein and A Eastman

PDF

Neurospora Crassa Clock-Controlled Genes are Regulated at the Level of Transcription., Jennifer J. Loros and Jay C. Dunlap

PDF

Serum Amyloid A (SAA3) Produced by Rabbit Synovial Fibroblasts Treated with Phorbol Esters or Interleukin 1 Induces Synthesis of Collagenase and is Neutralized with Specific Antiserum, T I. Mitchell, C I. Coon, and C E. Brinckerhoff

PDF

Acquired Cisplatin Resistance in Human Ovarian Cancer Cells is Associated with Enhanced Repair of Cisplatin-DNA Lesions and Reduced Drug Accumulation., Ricardo J. Parker, Alan Eastman, Frieda Bostick-Bruton, and Eddie Reed

PDF

Physiological Basis for Differential Sensitivities of Plant Species to Protoporphyrinogen Oxidase-Inhibiting Herbicides, Timothy D. Sherman, José M. Becerril, Hiroshi Matsumoto, Mary V. Duke, Judy M. Jacobs, Nicholas J. Jacobs, and Stephen O. Duke

PDF

Interleukin-1 or Phorbol Induction of the Stromelysin Promoter Requires an Element that Cooperates with AP-1., Karen Sirum-Connolly and Constance E. Brinckerhoff

PDF

Translocation of the Glucose Transporter GLUT4 in Cardiac Myocytes of the Rat., Jan W. Slot, Hans J. Geuze, Sander Gigengack, David E. James, and Gustav E. Lienhard

PDF

The Landmark Citation Method: Analysis of a Citation Pattern as a Collection Assessment Method, Catherine B. Soehner, S Tanner Wray, and Daniel T. Richards

PDF

Effect of Delays in Processing on the Survival of Mycobacterium Avium-M. Intracellulare in the Isolator Blood Culture System., C. Fordham von Reyn, Stephen Hennigan, Sandra Niemczyk, and Nicholas J. Jacobs

PDF

The Ability of Simian Virus 40 Large T Antigen to Immortalize Primary Mouse Embryo Fibroblasts Cosegregates with its Ability to Bind to P53., Jiyue Y. Zhu, Marina Abate, Philip W. Rice, and Charles N. Cole

PDF

Mapping the Transcriptional Transactivation Function of Simian Virus 40 Large T Antigen., Jiyue Y. Zhu, Philip W. Rice, Michele Chamberlain, and Charles N. Cole

PDF

Interleukin-2-Triggered Raf-1 Expression, Phosphorylation, and Associated Kinase Activity Increase through G1 and S in CD3-Stimulated Primary Human T Cells., Antanina Zmuidzinas, Harvey J. Mamon, Thomas M. Roberts, and Kendall A. Smith

Submissions from 1990

PDF

Nucleotide Sequence of the Epsilon-Subunit of the Mouse Muscle Nicotinic Acetylcholine Receptor, P D. Gardner

PDF

Monocytes and Polymorphonuclear Neutrophils of Patients with Streptococcal Pharyngitis Express Increased Numbers of Type I IgG Fc Receptors., Paul M. Guyre, A Scott Campbell, Wayne D. Kniffin, and Michael W. Fanger

PDF

N-Ethylmaleimide-Sensitive Protein(s) Involved in Cortical Exocytosis in the Sea-Urchin Egg - Localization to Both Cortical Vesicles and Plasma-Membrane, Robert C. Jackson and Paul A. Modern

PDF

Induction of Antigen-Specific Human Cytotoxic T Cells by Toxoplasma Gondii, I A. Khan, K A. Smith, and L H. Kasper

PDF

A Rapid and Simple Method for Preparation of RNA from Saccharomyces cerevisiae, Mark E. Schmitt, Timothy A. Brown, and Bernard L. Trumpower

PDF

Murine Gamma Interferon Fails to Inhibit Toxoplasma gondii Growth in Murine Fibroblasts., Joseph D. Schwartzman, Steven L. Gonias, and E R. Pfefferkorn

PDF

The Growth of Simian Virus 40 (SV40) Host Range/Adenovirus Helper Function Mutants in an African Green Monkey Cell Line that Constitutively Expresses the SV40 Agnoprotein., Terryl P. Stacy, Michele Chamberlain, Susan Carswell, and Charles N. Cole

PDF

International Travel and Hiv-Infection, C F. von Reyn, J M. Mann, and J Chin

PDF

Fibril in Senile Systemic Amyloidosis is Derived from Normal Transthyretin., Per Westermark, Knut Sletten, Bjorn Johansson, and Gibbons G. Cornwell

PDF

Mechanism of Escape of Endogenous Murine Leukemia Virus EMV-14 from Recognition by Anti-AKR/Gross Virus Cytolytic T Lymphocytes., Hillary D. White, Michael D. Robbins, and William R. Green

Submissions from 1989

PDF

Identification of Stage-Specific Antigens of Toxoplasma Gondii., Lloyd H. Kasper